Hypoglycemic and Hypotensive Effects of Calycotome villosa Subsp. intermedia Seeds in Meriones shawi Rats: In Vivo, Ex Vivo, and In Vitro Investigations

Table 1

Effect of sedentary lifestyle associated with the high-calorie diet for 12 weeks on fasting blood glucose, total cholesterol, triglycerides, and body weight.

Parameters	Treatment duration (weeks)
	0	2	4	6	8	10	12
Blood glucose (mg/dL)	76.00 ± 4.53	92.00 ± 5.65	99.10 ± 4.36	148.50 ± 7.77	175.50 ± 6.36^a	198.00 ± 5.65^a	222.00 ± 7.0^a
Total cholesterol (mmol/L)	1.21 ± 0.06	1.56 ± 0.02^b	1.86 ± 0.03^b	2.21 ± 0.03^b	2.49 ± 0.05^b	2.95 ± 0.08^b	3.19 ± 0.06^b
Triglycerides (mmol/L)	0.58 ± 0.04	0.60 ± 0.02	0.69 ± 0.03	0.79 ± 0.05^c	1.11 ± 0.04^c	1.24 ± 0.06^c	1.39 ± 0.08^c
Body weight (g)	103 ± 7.15	n.p	145 ± 10.33^d	n.p	182 ± 8.16^d	n.p	219 ± 8.5^d

a: comparison of blood glucose level between week 0 and all weeks, b: comparison of total cholesterol between week 0 and all weeks, c: comparison of triglycerides between week 0 and all weeks, d: comparison of body weight between week 0 and all weeks (, , and ). n.p: not performed.