Hypoglycemic and Hypotensive Effects of Calycotome villosa Subsp. intermedia Seeds in Meriones shawi Rats: In Vivo, Ex Vivo, and In Vitro Investigations
Table 2
Blood glucose level changes during 180 minutes after a single oral administration of the CV extract in normal and treated animals.
Experimental groups
Blood glucose levels (mg/dl)-time (minutes)
−30
0
15
30
45
60
120
180
HCD/SLS+DW
203.00 ± 5.65bc
202.00 ± 7.1bc
254.00 ± 5.38abc
271.50 ± 6.1abc
259.00 ± 7.1abc
244.00 ± 7.4abc
236.00 ± 8.5abc
229.00 ± 10.6abc
NC + DW
85.00 ± 2.8c
83.00 ± 4.2c
146.00 ± 7.1a
202 ± 4.2ac
150.00 ± 5.6a
116 ± 5.3ac
89.00 ± 4.2c
84.00 ± 5.6c
NC + CV
85.00 ± 4.2
82.00 ± 5.4
130.00 ± 7.1a
169.00 ± 5.6ab
147.00 ± 8.5a
114.00 ± 7.1a
87.00 ± 4.2
84.00 ± 6.9
HCD/SLS + CV
213.00 ± 5.6b
207.00 ± 8.1b
152.00 ± 7.3
175.00 ± 7.1ab
157.00 ± 8.2a
148.00 ± 5.8ab
138.00 ± 5.6ab
134.00 ± 3.1ab
a: as compared to blood glucose level at 0 time, b: in comparison to normal groups, and c: in comparison to diabetic treated groups.