Hypoglycemic and Hypotensive Effects of Calycotome villosa Subsp. intermedia Seeds in Meriones shawi Rats: In Vivo, Ex Vivo, and In Vitro Investigations
Table 3
Effect of the CV extract on blood glucose, heartbeat, and systolic arterial pressure in normal and treated animals.
Parameters
Treatment duration (weeks)
Experimental groups
HCD/SLS + DW
NC + DW
NC + CV
HCD/SLS + CV
HCD/SLS + (Aml + )
Body weight (g)
0
221.00 ± 8.17
160.37 ± 2.60
171.75 ± 2.13
222.9 ± 6.83
225.00 ± 10.40
1
221.60 ± 6.97
156.25 ± 4.01
147.75 ± 2.28
202.3 ± 6.20
223.33 ± 8.81
2
222.40 ± 6.33
159.00 ± 2.92
221.66 ± 9.28
3
157.50 ± 3.17
Blood glucose (mg/dl)
0
220.00 ± 5.42
85.10 ± 4.10
84.18 ± 4.15
218.82 ± 6.10
228.10 ± 8.34
1
228.00 ± 9.82
83.75 ± 5.30
85.29 ± 4.73
219.40 ± 6.22
2
235.00 ± 9.89
87.60 ± 4.80
85.85 ± 4.45
3
84.75 ± 6.43
83.50 ± 4.49
Heart beat (nb/min)
0
330.00 ± 17.32
270.00 ± 0.00
300.00 ± 0.00
315.00 ± 15.00
300.00 ± 00.00
1
322.50 ± 22.50
270.00 ± 0.00
292.50 ± 7.50
307.50 ± 18.87
300.00 ± 00.00
2
319.00 ± 14.14
270.00 ± 0.00
285.00 ± 8.66
285.00 ± 8.66
280.00 ± 6.66
3
290.00 ± 8.66
SAP (mm Hg)
0
152.00 ± 4.24
106.00 ± 2.82
110.00 ± 4.12
149.00 ± 7.07
105.50 4.94
1
155.50 ± 3.53
105.50 ± 3.13
108.00 ± 3.56
145.00 ± 5.65
2
151.00 ± 5.65
104.50 ± 5.32
106.50 ± 5.41
3
107.00 ± 4.16
106.00 ± 4.73
a: comparison of variables between week 0 and all weeks, b: comparison between the normal group and all groups at week 3, c: comparison between the diabetic group (DC) and the treated diabetic group at week 3 (,, and ).
