Hypoglycemic and Hypotensive Effects of Calycotome villosa Subsp. intermedia Seeds in Meriones shawi Rats: In Vivo, Ex Vivo, and In Vitro Investigations
Table 5
Effect of the CV extract on urinary electrolyte (sodium, potassium, and chloride) levels in normal and treated animals.
Parameters
Treatment duration(weeks)
Experimental groups
HCD/SLS + DW
NC + DW
NC + CV
HCD/SLS + CV
HCD/SLS + (Aml + )
Urinary Na+ (mmol/24 h)
0
4.90 ± 0.14
3.40 ± 0.13
3.44 ± 0.09
5.09 ± 0.14
3.43 ± 0.09
1
5.05 ± 0.07
3.62 ± 0.14
3.68 ± 0.02
6.24 ± 0.16
2
4.71 ± 0.15
3.19 ± 0.14
3.18 ± 0.12
7.02 ± 0.15
3
3.51 ± 0.16
3.51 ± 0.08
Urinary K+ (mmol/24 h)
0
2.61 ± 0.09
1.44 ± 0.04
1.55 ± 0.07
2.52 ± 0.11
2.10 ± 0.12
1
2.80 ± 0.02
1.52 ± 0.05
1.45 ± 0.02
2.22 ± 0.16
2
2.46 ± 0.10
1.49 ± 0.08
1.47 ± 0.10
1.92 ± 0.16
3
1.42 ± 0.07
1.41 ± 0.05
Urinary Cl−(mmol/24 h)
0
5.04 ± 0.07
3.99 ± 0.07
4.00 ± 0.05
5.68 ± 0.09
3.68 ± 0.05
1
5.22 ± 0.05
4.01 ± 0.09
3.99 ± 0.10
2
4.09 ± 0.11
4.14 ± 0.02
3
4.02 ± 0.08
4.00 ± 0.10
a: comparison of variables between the week 0 and all weeks, b: comparison between the normal group and all groups at week 3, c: comparison between the diabetic group and the treated diabetic group at week 3 (,, and ).
