TP73-AS1 rs3737589 Polymorphism is Associated With the Clinical Stage of Colorectal Cancer

Table 3

Association between TP73-AS1 gene rs3737589 polymorphism and CRC susceptibility.

Genotype or allele	CRC patients (N = 576)	Healthy controls (N = 896)	^aOR (95% CI)	^a value
Genotype
TT	318 (55.2%)	508 (56.7%)	Reference
TC	213 (37.0%)	333 (37.2%)	1.03 (0.82–1.28)	0.85
CC	45 (7.8%)	55 (6.1%)	1.33 (0.87–2.03)	0.22
Ptrend				0.36
PHWE				0.97
TT	318 (55.2%)	508 (56.7%)	Reference	0.59
TC + CC	258 (44.8%)	388 (43.3%)	1.07 (0.86–1.32)
TT + TC	531 (92.2%)	841 (93.9%)	Reference	0.22
CC	45 (7.8%)	55 (6.1%)	1.32 (0.88–1.99)
Allele
T	849 (73.7%)	1349 (75.3%)	Reference	0.33
C	303 (26.3%)	443 (24.7%)	1.09 (0.92–1.29)

^aAdjusted for age and gender.