Research Article

Investigation of the Potential Mechanism of Alpinia officinarum Hance in Improving Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking

Table 1

The active components of A. officinarum.

IDsMolecule namesSourcesMWGI absorptionsLipinski rules

COM-1SitosterolTCMSP414.71LowYes
COM-2(2S,3R)-2-(3,4-Dimethoxyphenyl)-5,7-dimethoxychroman-3-olTCMSP346.37HighYes
COM-35-Hydroxy-1,7-diphenyl-3-heptanoneTCMSP282.38HighYes
COM-41-Hydroxy-1,7-bis (4-hydroxy-3-methoxyphenyl)-6-heptene-3,5-dioneETCM386.4HighYes
COM-55-Hydroxy-7-(4″-hydroxy-3″-methoxy-phenyl)-1-phenyl-3-heptanonePubMed328.4HighYes
COM-65-Methoxy-1,7-diphenyl-3-heptanoneTCMSP296.4HighYes
COM-75-Methoxy-7-(4″-hydroxyphenyl)-1-phenyl-3-heptanoneBATMAN-TCM312.4HighYes
COM-85R-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-3-heptanonePubMed344.4HighYes
COM-97-(4″-Hydroxy-3″-methoxyphenyl)-1-phenyl-hept-4-en-3-onePubMed310.39HighYes
COM-107-Hydroxy-3,5-dimethoxyflavoneETCM298.29HighYes
COM-117-Methoxy-8-(2′-ethoxy-3′-hydroxy-3′-methybutyl) coumarinTCMSP292.33HighYes
COM-12AzaleatinETCM316.26HighYes
COM-13Beta-sitosterolTCMSP414.71LowYes
COM-14Butyl-2-ethylhexyl phthalateTCMSP348.48HighYes
COM-15Delta-cadineneBATMAN-TCM204.35LowYes
COM-16EucalyptolBATMAN-TCM154.25HighYes
COM-17EugenolBATMAN-TCM164.2HighYes
COM-18GalanginETCM, BATMAN-TCM, TCMSP270.24HighYes
COM-19GalanolactoneBATMAN-TCM318.45HighYes
COM-20GuaiacolETCM124.14HighYes
COM-21HexahydrocurcuminBATMAN-TCM374.43HighYes
COM-22IsorhamnetinTCMSP316.26HighYes
COM-23KaempferideETCM300.26HighYes
COM-24KaempferolBATMAN-TCM, TCMSP286.24HighYes
COM-25MedicarpinBATMAN-TCM, TCMSP270.28HighYes
COM-26MethylcinnamateBATMAN-TCM162.19HighYes
COM-27OctahydrocurcuminBATMAN-TCM376.44HighYes
COM-28ClionasterolTCMSP414.71LowYes
COM-29QuercetinETCM, BATMAN-TCM, TCMSP302.24HighYes