Rutin and Hesperidin Alleviate Paclitaxel-Induced Nephrocardiotoxicity in Wistar Rats <i>via</i> Suppressing the Oxidative Stress and Enhancing the Antioxidant Defense Mechanisms

<div>Photomicrographs of the kidney sections of the normal (a), paclitaxel-administered control group (b), and paclitaxel-administered groups treated with rutin (c), hesperidin (d), and their combination (e). G: glomeruli; PT: proximal tubules; DT: distal tubules; DC: degenerative changes; IC: inflammatory cells infiltration; FP: fibroblastic proliferation (H&amp;E; ×400).</div>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Rutin and Hesperidin Alleviate Paclitaxel-Induced Nephrocardiotoxicity in Wistar Rats <i>via</i> Suppressing the Oxidative Stress and Enhancing the Antioxidant Defense Mechanisms 

Figure 6 | Rutin and Hesperidin Alleviate Paclitaxel-Induced Nephrocardiotoxicity in Wistar Rats via Suppressing the Oxidative Stress and Enhancing the Antioxidant Defense Mechanisms 