Polyphyllin I Effects Candida albicans via Inhibition of Virulence Factors

Figure 5

Exogenous cAMP restores the hyphal formation of C . albicans, which is inhibited by PPI. Images were photographed (40x magnification) after incubation in two different hyphae-inducing media at 37°C for 4 h and 8 h. (a) Exogenous cAMP restored PPI-inhibited hyphal formation in Spider medium with or without db-cAMP for 4 h and 8 h. (b) Exogenous cAMP restored PPI-inhibited hyphal formation in SD + 10% FBS medium with or without db-cAMP for 4 h and 8 h.

(a)

(b)