Polyphyllin I Effects Candida albicans via Inhibition of Virulence Factors

Table 2

MIC_50s of PPI and FLC against C. albicans.

C. albicans	MIC50 (μg/mL)
	FLC	PPI
CA23	>200	2.00 ± 0.31
CA187	>200	0.95 ± 0.06
CA5408	>200	6.36 ± 0.94
CA3511	>200	4.37 ± 0.01
CA800	>200	3.26 ± 0.17
CA602	>200	46.00 ± 1.30
CA799	>200	>200
CA558	>200	>200
CA3816	>200	>200
ATCC10231-FR	>200	0.90 ± 0.01
SC5314-FR	>200	0.98 ± 0.01

FLC, fluconazole; PPI, polyphyllin I; CA, C. albicans. MIC₅₀ was defined as the 50% inhibition of fungal growth compared to control group growth; the data are shown as mean ± SD.