Evidence-Based Complementary and Alternative Medicine

Review Article

To Investigate the Clinical Efficacy and Potential Mechanism of Tongxinluo Capsules in Preventing Coronary Restenosis Based on Meta-Analysis and Network Pharmacology Analysis

Table 2

List of main chemical constituents of Tongxinluo capsules.
PubChem CIDCompoundsMolecular formulaMedicinal materialsReference value
33934DiopC24H38O4GinsengOB ≥ 30%, DL ≥ 0.18
5280794StigmasterolC29H48OGinseng\radix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
222284Beta-sitosterolC29H50OGinseng\radix paeoniae rubra\rosewood heart woodOB ≥ 30%, DL ≥ 0.18
91510InerminC16H12O5GinsengOB ≥ 30%, DL ≥ 0.18
5280863KaempferolC15H10O6GinsengOB ≥ 30%, DL ≥ 0.18
5319581ScopolamineC16H12NO3GinsengOB ≥ 30%, DL ≥ 0.18
285342DeoxyharringtonineC28H37NO8GinsengOB ≥ 30%, DL ≥ 0.18
441562DianthramineC14H11NO6GinsengOB ≥ 30%, DL ≥ 0.18
5312542ArachidonateC20H32O2GinsengOB ≥ 30%, DL ≥ 0.18
441965Frutinone AC16H8O4GinsengOB ≥ 30%, DL ≥ 0.18
119307Ginsenoside rh2C36H62O8GinsengOB ≥ 30%, DL ≥ 0.18
—Ginsenoside-Rh4_qtC36H60O8GinsengOB ≥ 30%, DL ≥ 0.18
96943GirinimbineC18H17NOGinsengOB ≥ 30%, DL ≥ 0.18
73498PanaxadiolC30H52O3GinsengOB ≥ 30%, DL ≥ 0.18
132350840SuchilactoneC21H20O6GinsengOB ≥ 30%, DL ≥ 0.18
—Alexandrine_qtC35H60O6GinsengOB ≥ 30%, DL ≥ 0.18
4970FumarineC20H19NO5GinsengOB ≥ 30%, DL ≥ 0.18
5280445LuteolinC15H10O6SandalwoodOB ≥ 30%, DL ≥ 0.18
5281654IsorhamnetinC16H12O7SandalwoodOB ≥ 30%, DL ≥ 0.18
162350IsovitexinC21H20O10SandalwoodOB ≥ 30%, DL ≥ 0.18
72Protocatechuic acidC7H6O4Cicada sloughOB ≥ 30%, DL ≥ 0.18
16072146N-[(E)-2-[(2R,3S)-3-acetamido-2-(3,4-dihydroxyphenyl)-2,3-dihydro-1,4-benzodioxin-7-yl]vinyl]acetamideC20H20N2O6Cicada sloughOB ≥ 30%, DL ≥ 0.18
6437642(3Z)-3-(2-amino-4,6-dioxo-5,8-dihydro-1H-pteridin-7-ylidene)-2-oxopropanoic acidC20H20N2O6Cicada sloughOB ≥ 30%, DL ≥ 0.18
8768ProtocatechualdehydeC7H6O3Cicada sloughOB ≥ 30%, DL ≥ 0.18
774HistamineC5H9N3CentipedeScore ≥ 20,
1153TyrosinC9H11NO3CentipedeScore ≥ 20,
6274L-HistidineC6H9N3O2CentipedeScore ≥ 20,
5997CholesterolC27H46OCentipede/scorpio/woodlouseScore ≥ 20,
6106LeucineC6H13NO2CentipedeScore ≥ 20,
—StearinC21H42O4ScorpioScore ≥ 20,
531803520-Hexadecanoyl-Ingenol—ScorpioScore ≥ 20,
1123TaurineC2H7NO3SScorpioScore ≥ 20,
1146TrimethylamineC3H9NScorpioScore ≥ 20,
5281233CrocinC44H64O24LeechScore ≥ 20,
24721095GardenosideC17H24O11LeechScore ≥ 20,
64945Ursolic acidC30H48O3LeechScore ≥ 20,
107848GeniposideC17H24O10LeechScore ≥ 20,
11850DulcitolC6H14O6LeechScore ≥ 20,
10508035Gardnerilin AC35H66O8LeechScore ≥ 20,
6251D-MannitolC6H14O6LeechScore ≥ 20,
772EnoxaparinC26H42N2O37S5LeechScore ≥ 20,
5281232CrocetinC20H24O4LeechScore ≥ 20,
—HeparinC26H42N2O37S5LeechScore ≥ 20,
772NadroparinC26H42N2O37S5LeechScore ≥ 20,
12600D-MannoheptuloseC7H14O7LeechScore ≥ 20,
5459879L-GalactoheptuloseC7H14O7LeechScore ≥ 20,
3080632Stigmast-7-en-3-olC29H50ORadix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
—(2R,3R)-4-methoxyl-distylinC16H17O7Radix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
173183Campest-5-en-3beta-olC28H48ORadix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
5281331SpinasterolC29H48ORadix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
5363269Ethyl oleate (NF)C20H38O2Radix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
64982BaicalinC21H18O11Radix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
5281605BaicaleinC15H10O5Radix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
442534PaeoniflorinC23H28O11Radix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
—PaeoniflorgenoneC18H22O6Radix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
5281855Ellagic acidC14H6O8Radix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
9064(+)-catechinC15H14O6Radix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
12303645SitosterolC29H50ORadix paeoniae rubraOB ≥ 30%, DL ≥ 0.18
667495(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-oneC15H12O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
114829DFVC15H12O4Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
821279(2R)-7-hydroxy-5-methoxy-2-phenylchroman-4-oneC16H14O4Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
336327MedicarpinC16H14O4Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
373261Eriodyctiol (flavanone)C15H12O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
5319494(3R)-4′-Methoxy-2′,3,7-trihydroxyisoflavoneC16H14O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
14353662(3R)-3-(2,3-dihydroxy-4-methoxyphenyl)-7-hydroxychroman-4-oneC16H14O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
14353660(3R)-3-(2,3-dihydroxy-4-methoxyphenyl)chroman-7,8-diolC16H16O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
—(3R)-7,2′,3′-trihydroxy-4-methoxyisoflavanC16H16O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
53195659-O-MethylcoumestrolC16H10O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
53194223′-MethoxydaidzeinC16H12O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
182259(−)-VestitolC16H16O4Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
10019512(3S)-7-hydroxy-3-(2,3,4-trimethoxyphenyl) chroman-4-oneC18H18O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
—4′,5',7-trimethyl-3-methoxyflavoneC19H118O3Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
442768DalberginC16H12O4Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
—7-hydroxy-4′-methoxy-2′,5′-dioxo-4-[(3R)-2',7-dihydroxy-4′-methoxyisoflavan-5′-yl]isoflavoneC32H127O9Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
28125525ButinC15H12O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
127790DuartinC18H20O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
10065329IsoduartinC18H20O6Rosewood heart woodOB ≥ 30%,
4427924-HydroxyhomopterocarpinC17H16O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
23259932(6aR,11aR)-3,9,10-trimethoxy-6a,11a-dihydro-6H-benzofurano [3,2-c]chromen-4-olC18H18O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
23259933(6aR,11aR)-3,9-dimethoxy-6a,11a-dihydro-6H-benzofurano[3,2-c] chromene-4,10-diolC17H16O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
32990315OdoricarpinC18H18O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
5321142SativanoneC17H16O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
5321501SteveinC16H12O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
44446897VestitoneC16H14O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
44446884ViolanoneC17H16O6Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
5280551Xenognosin BC16H12O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
14077830(6aR,11aR)-9,10-dimethoxy-6a,11a-dihydro-6H-benzofurano [3,2-c]chromen-3-olC17H16O5Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
5280378FormononetinC16H12O4Rosewood heart woodOB ≥ 30%, DL ≥ 0.18
101257TirucallolC30H50OFrankincenseOB ≥ 30%, DL ≥ 0.18
—O-acetyl-α-boswellic acidC₃₀H₄₈O₃FrankincenseOB ≥ 30%, DL ≥ 0.18
—3alpha-Hydroxy-olean-12-en-24-oic-acid FrankincenseOB ≥ 30%, DL ≥ 0.18
9847548Boswellic acidC30H46O4FrankincenseOB ≥ 30%, DL ≥ 0.18
520687PhyllocladeneC20H32FrankincenseOB ≥ 30%, DL ≥ 0.18
160487(S)-CoclaurineC17H19NO3Spina date seedOB ≥ 30%, DL ≥ 0.18
5742590DaucosterolC35H60O6Spina date seedOB ≥ 30% DL ≥ 0.18,
222284PhytosterolC29H50OSpina date seedOB ≥ 30%, DL ≥ 0.18
14729078SanjoinenineC29H35N3O4Spina date seedOB ≥ 30%, DL ≥ 0.18
124034SwertisinC22H22O10Spina date seedOB ≥ 30%, DL ≥ 0.18
102063083ZizyphusineC20H24NO4+Spina date seedOB ≥ 30%, DL ≥ 0.18
64971MairinC30H48O3Spina date seedOB ≥ 30%, DL ≥ 0.18
119034Asiatic acidC30H48O5BorneolOB ≥ 30%, DL ≥ 0.18