To Investigate the Clinical Efficacy and Potential Mechanism of Tongxinluo Capsules in Preventing Coronary Restenosis Based on Meta-Analysis and Network Pharmacology Analysis

Table 3

Topology parameter analysis of protein interaction (top 30).

Gene	Connectivity	Intermediate centrality	Closeness centrality	Topological parameter
TNF	44.81000	0.043298	0.740000	0.311181
IL-6	45.12121	0.040793	0.740000	0.311181
ALB	44.48485	0.078305	0.743719	0.304691
AKT1	46.58763	0.038277	0.736318	0.319093
INS	46.39130	0.047215	0.718447	0.317749
TP53	49.39080	0.026911	0.694836	0.342992
VEGFA	51.53012	0.012023	0.678899	0.360350
IL1B	50.09756	0.017848	0.678899	0.347900
PTGS2	50.69512	0.025018	0.678899	0.352049
JUN	51.80247	0.018249	0.675799	0.359739
EGFR	50.87342	0.015414	0.666667	0.355758
CASP3	53.14103	0.011855	0.663677	0.371616
MMP9	52.60256	0.012034	0.657778	0.373068
PPARG	50.66234	0.022659	0.663677	0.351822
FOS	52.02740	0.027691	0.654867	0.358810
CXCL8	53.74286	0.007951	0.637931	0.378471
ESR1	53.15942	0.011699	0.640693	0.369163
NOS3	49.56522	0.049894	0.637931	0.346610
CCL2	55.28788	0.005754	0.629787	0.386629
IGF1	55.68182	0.008738	0.629787	0.389383
CCND1	54.86154	0.007079	0.619247	0.391868
ICAM1	56.01563	0.004671	0.621849	0.394476
SIRT1	53.71429	0.012423	0.621849	0.375624
MAPK8	55.42857	0.005980	0.624473	0.384921
MMP2	57.70492	0.005082	0.609054	0.412178
CAT	53.2459	0.033342	0.616667	0.374856
ACE	49.7500	0.028737	0.616667	0.345486
MAPK1	51.67797	0.009489	0.611570	0.361384