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No. | Study | Type of intervention | Duration, frequency, and duration of intervention | Evaluated results |
Intervention | Control |
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1 | Surabhi Gautam | Yoga (NE) | 8 weeks of yoga practice, 120 minute sessions, plus FARME | Continuation of formulated FARMEs | Measurement of changes in disease activity through DAS 28. Assessment of mitochondrial health status. Measurement of functional changes |
2 | Selvakumar Ganesan | Yoga (NE) | 12 weeks of yoga practice, 30-minute sessions 3 times a week, plus FARME | Continuation of formulated FARMEs | Measurement of disease activity through DAS 28, inflammatory markers, and heart rate variability |
3 | Madhuri Tolahunasea | Yoga (Patanjali’s Raj yoga) | 8 weeks of yoga practice, 120 minute sessions 5 times per week, plus FARME | Continuation of formulated FARMEs | Assess change in RA severity through DAS 28, inflammatory markers, pro- and anti-inflammatory cytokines, and immunomodulatory markers |
4 | Wen-zhong Cao | Acupuncture (NE) | Triple therapy administered every 3 days consecutively for 10 times for 30 days, plus DMARDs | Methotrexate 10 mg weekly, diclofenac 0.3 gr dose, folic acid 5 mg weekly for 30 days | Measurement of changes in disease activity through RF, DAS 28, CRP, and ESR |
5 | Zhu Yan | Acupuncture (NE) | Basic points stimulated were Ganshu, Shenshu, Hegu, Quchi, and Zusanli, administered every day for 6 consecutive days a week for 3 courses, associated with FARME | Methotrexate 10 mg weekly, ibuprofen 0.3 g twice a day, folic acid 5 mg weekly; one course of treatment equivalent to 30 days, and 3 courses were necessary | Measurement of serological indices, changes in disease activity through DAS 28, observation of signs and/or symptoms of blood stasis, and assessment of active symptomatology through qualitative measurement |
6 | Manoj Kumar | Yoga (Patanjali’s Ashtanga) | 8 weeks of practice with Patanjali’s Ashtanga yoga component, 120-minute sessions 5 times a week, plus FARME | Continuation of formulated FARMEs | Measurement of changes in disease activity through DAS 28, inflammatory markers, mind-body communication markers, and assess changes in quality of life |
7 | Xie Yu-ying | Acupuncture (electro) | 1 session every 2 days for 12 weeks, plus formulated DMARDs + NSAIDs (control group scheme) | Methotrexate 10–12.5 mg weekly, nimesulide 0.1 mg twice a day, omeprazole 100 mg 3 times a day depending on the patient | Assessment of active symptomatology through qualitative measurement, DAS 28, ESR, CRP, and evaluation of efficacy |
8 | Atef M | Acupuncture (laser) | Laser acupuncture (904 nm, output power 100 mW, irradiation time 1 minute), 3 days a week for 4 weeks | No intervention, healthy patients | Measurement of disease activity through DAS 28, RF, inflammation markers, oxidation markers, antioxidant enzymes, and ATP levels |
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