Research Article

Effect of Proprietary Chinese Medicine on Coronary Microvascular Dysfunction in Patients with Microvascular Angina: A Systematic Review and Meta-Analysis

Table 3

Subgroup analysis of IMR based on dosage form, sample size, treatment duration, sex ratio, average age, and location.

ItemsSubgroupnSMD (95% CI)I 2 (%)z

Dosage formPill3−1.98 (−3.15, −0.82)91.8−3.3270.001
Dropping pill2−1.75 (−3.82, 0.32)97.8−1.6550.098
Capsule1−1.31 (−1.77, −0.84)−5.515<0.001

Sample size≥802−2.06 (−3.52, −0.59)95.6−2.7560.006
<804−1.65 (−2.64, −0.66)92.3−3.2760.001

Treatment duration≥6 months5−1.51 (−2.29, −0.73)92.5−3.801<0.001
<6 months1−1.79 (−2.58, −1.00)−9.373<0.001

Sex ratioF/M ≥ 100%2−2.42 (−4.05, −0.79)92.9−2.9130.004
F/M < 100%4−1.49 (−2.47, −0.51)94.4−2.9810.003

Average age>603−2.24 (−3.79, −0.69)96.5−2.8340.005
<603−1.34 (−1.63, −1.05)0.0−8.960<0.001

LocationNorth3−2.39 (−3.61, −1.18)93.8−3.861<0.001
South3−1.19 (−1.71, −0.67)70.4−4.455<0.001