Research Article

Effect of a Standardized Extract of Asparagus officinalis Stem (ETAS®50) on Cognitive Function, Psychological Symptoms, and Behavior in Patients with Dementia: A Randomized Crossover Trial

Table 2

Between-group comparisons of the initial and final scores and differences in scores for each assessment method (n = 27).

ETAS®50 period
InitialFinalDifference

MMSE21.00 ± 5.1921.48 ± 5.690.48 ± 2.33
CDT11.60 ± 4.3311.80 ± 4.51−0.28 ± 4.23
NPI-Q-a2.50 ± 3.441.96 ± 3.23−0.56 ± 1.72
NPI-Q-b2.70 ± 4.642.48 ± 4.76−0.26 ± 1.29
QOL42.89 ± 5.0342.89 ± 4.930.00 ± 3.57
SDS34.93 ± 6.3534.56 ± 7.44−0.37 ± 4.56

Placebo periodDifferencevalue
InitialFinalDifference

21.11 ± 5.0621.00 ± 5.97−0.11 ± 2.680.420
11.80 ± 3.7511.89 ± 4.640.09 ± 2.490.827
2.20 ± 3.302.89 ± 4.850.67 ± 2.340.045
2.60 ± 4.423.00 ± 5.970.44 ± 2.310.472
43.37 ± 4.7243.56 ± 4.710.19 ± 4.200.903
34.89 ± 7.3832.82 ± 7.02−2.07 ± 6.700.327

values <0.05 compared to the initial and final scores are considered statistically significant.