Evidence-Based Complementary and Alternative Medicine

Herbal Medicine Development: Methodologies, Challenges, and Issues


Status
Closed

Lead Editor

1Nagasaki University, Nagasaki, Japan

2GCP Alliance, Brussels, Belgium

3Thamasart University, Bangkok, Thailand

4UP Manila, Manila, Philippines

This issue is now closed for submissions.
More articles will be published in the near future.

Herbal Medicine Development: Methodologies, Challenges, and Issues

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Herbal medicines have been used in traditional medical practices for centuries; however, the development of herbal medicine within an evidence-based medicine’s framework is relatively new. Demonstrating the safety and efficacy of such medicines is fraught with challenges and criticisms, especially when compared with “Western chemical medical compounds.” While practitioners of herbal medicine are often not only comfortable with the application of such medicines but also largely convinced by the results they experience with patients, the scientific validity of herbal medicines in research and development is still often questioned. This is partly due to the application of similar methodologies across dissimilar medical products as well as to a lack of quality control and product standardization.

The application of contemporary evidence-based approaches, particularly controlled clinical trials, has presented specific challenges and issues for herbal medicines in R&D. There is a need to follow the acceptable standards in the conduct of herbal medicine R&D, while also taking into account the complexity of the chemical composition of herbal medicines and their use in the framework of traditional medical practices. Research design and the conduct of research must be scientifically and ethically sound, while also accounting for the medical philosophies and practices that accompany the use of traditional medicines.

This Special Issue intends to identify current issues in herbal medicine development in different settings, to examine the methodological challenges, and to discuss the regulatory and ethical issues that arise, both in nonclinical and clinical research. The objective of this special issue is to examine the current state of the art for herbal medicines R&D while identifying appropriate methodologies to address issues and challenges for developing herbal medicine under the acceptable scientific and ethical standards.

Potential topics include but are not limited to the following:

  • Current and prospective methodologies for testing herbal medicines in nonclinical and clinical settings
  • Herbal product quality control and assurance
  • Intellectual property
  • Regulatory issues
  • Ethical issues
  • Informed consent in herbal medicine research
  • Ethnopharmacology
  • Nonclinical studies
  • Clinical studies
  • Data management issues
  • Phytochemistry
  • Drug formulation

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 4935786
  • - Editorial

Herbal Medicine Development: Methodologies, Challenges, and Issues

Juntra Karbwang | Francis P. Crawley | ... | Cecilia Maramba-Lazarte
  • Special Issue
  • - Volume 2018
  • - Article ID 6391414
  • - Research Article

Optimization of Bioactive Ingredient Extraction from Chinese Herbal Medicine Glycyrrhiza glabra: A Comparative Study of Three Optimization Models

Li Yu | Weifeng Jin | ... | Yuyan Zhang
  • Special Issue
  • - Volume 2018
  • - Article ID 2719794
  • - Review Article

Effects of Panax ginseng on Obesity in Animal Models: A Systematic Review and Meta-Analysis

Hye-Sung Park | Jae-Heung Cho | ... | Mi-Yeon Song
  • Special Issue
  • - Volume 2018
  • - Article ID 9707543
  • - Research Article

Prevention of Prostate Tumor Development by Stimulation of Antitumor Immunity Using a Standardized Herbal Extract (Deep Immune®) in TRAMP Mice

Peihe Liang | Jia Guo | ... | Caigan Du
  • Special Issue
  • - Volume 2018
  • - Article ID 6857398
  • - Research Article

Long-Zhi Decoction Medicated Serum Promotes Angiogenesis in Human Umbilical Vein Endothelial Cells Based on Autophagy

Quan He | Qihua Liu | ... | Ling Zou
  • Special Issue
  • - Volume 2018
  • - Article ID 9431819
  • - Research Article

Formulation and Characterization of Potential Antifungal Oleogel with Essential Oil of Thyme

Giedre Kasparaviciene | Zenona Kalveniene | ... | Jurga Bernatoniene
  • Special Issue
  • - Volume 2018
  • - Article ID 8384631
  • - Research Article

Gynostemma pentaphyllum Attenuates the Progression of Nonalcoholic Fatty Liver Disease in Mice: A Biomedical Investigation Integrated with In Silico Assay

Ming Hong | Zhe Cai | ... | Xiangfei Feng
  • Special Issue
  • - Volume 2018
  • - Article ID 8132798
  • - Review Article

Ma-Huang-Fu-Zi-Xi-Xin Decoction for Allergic Rhinitis: A Systematic Review

Juan Zhong | Dan Lai | ... | Gang Li
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate27%
Submission to final decision68 days
Acceptance to publication33 days
CiteScore2.900
Impact Factor1.813
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