Evidence-Based Complementary and Alternative Medicine

Use of Medicinal Plants and Natural Products for Treatment of Osteoporosis and its Complications


Publishing date
30 Nov 2012
Status
Published
Submission deadline
13 Jul 2012

1Department of Pharmacology, The National University of Malaysia (UKM), Kuala Lumpur, Malaysia

2Department of Anatomy, The National University of Malaysia (UKM), Kuala Lumpur, Malaysia

3Department of Nutrition & Food Sciences, Texas Women's University, Texas, TX, USA


Use of Medicinal Plants and Natural Products for Treatment of Osteoporosis and its Complications

Description

Osteoporosis is characterized by low bone mass with susceptibility to fracture. It may only be discovered when fractures of the osteoporotic bone have occurred. Therefore, prevention and early treatment of osteoporosis are important to avoid its complications. Some of the anti-osteoporotic drugs available are associated with serious side effects. The best example is estrogen replacement therapy, which was reported to increase the risks of breast cancer, uterine cancer, stroke, and cardiovascular and thromboembolic diseases (WHI Study, 2003). Researches are on the way to find alternative anti-osteoporotic agents with comparable effectiveness but with minimal side effects. It is to be hoped that the increased ethnobotanical and ethnopharmacological researches will lead to the development of novel drug candidates.

We invite investigators to submit review articles and original research that evaluate the role of medicinal plants and natural products on the treatment and prevention of osteoporosis and its complications such as fractures and deformities. We are particularly interested in articles that explore aspects of anti-osteoporosis using animals and human studies. Potential topics include, but are not limited to:

  • Studies using in vivo and in vitro models of osteoporosis for assessments of their anti-osteoporotic activities and their possible mechanisms of action
  • Human studies on the use of medicinal plants and natural products for the prevention and treatment of osteoporosis or osteopenia
  • Role of the medicinal plants and natural products on the phases of osteoporotic fracture healing, that is, the reactive, repair, and remodeling phases
  • Comparison of the efficacy of the medicinal plants and natural products with the standard anti-osteoporotic drugs using animal models or clinical trials
  • Elucidating the active ingredients, the mechanism of action, and potential toxicities of these medicinal plants and natural products
  • Elucidating the role of inflammation and oxidative stress in osteoporosis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ecam/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 656025
  • - Research Article

Effects of Palm Vitamin E on Bone-Formation-Related Gene Expression in Nicotine-Treated Rats

Seham Salem Ahmed Abukhadir | Norazlina Mohamed | ... | Norliza Muhammad
  • Special Issue
  • - Volume 2012
  • - Article ID 818072
  • - Research Article

Effects of Eurycoma longifolia on Testosterone Level and Bone Structure in an Aged Orchidectomised Rat Model

Abdul Shukor Tajul Ariff | Ima Nirwana Soelaiman | ... | Ahmad Nazrun Shuid
  • Special Issue
  • - Volume 2012
  • - Article ID 680834
  • - Research Article

Effects of Low-Dose versus High-Dose γ-Tocotrienol on the Bone Cells Exposed to the Hydrogen Peroxide-Induced Oxidative Stress and Apoptosis

Nizar Abd Manan | Norazlina Mohamed | Ahmad Nazrun Shuid
  • Special Issue
  • - Volume 2012
  • - Article ID 501858
  • - Research Article

Bone Micro-CT Assessments in an Orchidectomised Rat Model Supplemented with Eurycoma longifolia

Rosmaliza Ramli | Mohd Fadhli Khamis | Ahmad Nazrun Shuid
  • Special Issue
  • - Volume 2012
  • - Article ID 525079
  • - Research Article

The Effects of Virgin Coconut Oil on Bone Oxidative Status in Ovariectomised Rat

Mouna Abdelrahman Abujazia | Norliza Muhammad | ... | Ima Nirwana Soelaiman
  • Special Issue
  • - Volume 2012
  • - Article ID 960742
  • - Research Article

Effects of Tocotrienol and Lovastatin Combination on Osteoblast and Osteoclast Activity in Estrogen-Deficient Osteoporosis

Saif Abdul-Majeed | Norazlina Mohamed | Ima-Nirwana Soelaiman
  • Special Issue
  • - Volume 2012
  • - Article ID 872406
  • - Research Article

Combined Effects of Eurycoma longifolia and Testosterone on Androgen-Deficient Osteoporosis in a Male Rat Model

Halimatun Saadiah Abdul Razak | Ahmad Nazrun Shuid | Isa Naina Mohamed
  • Special Issue
  • - Volume 2012
  • - Article ID 817814
  • - Research Article

The Effects of Cosmos caudatus on Structural Bone Histomorphometry in Ovariectomized Rats

Norazlina Mohamed | Sharon Gwee Sian Khee | ... | Ima-Nirwana Soelaiman
  • Special Issue
  • - Volume 2012
  • - Article ID 747020
  • - Review Article

Vitamin E as an Antiosteoporotic Agent via Receptor Activator of Nuclear Factor Kappa-B Ligand Signaling Disruption: Current Evidence and Other Potential Research Areas

Kok-Yong Chin | Soelaiman Ima-Nirwana
  • Special Issue
  • - Volume 2012
  • - Article ID 125761
  • - Review Article

Eurycoma longifolia: Medicinal Plant in the Prevention and Treatment of Male Osteoporosis due to Androgen Deficiency

Nadia Mohd Effendy | Norazlina Mohamed | ... | Ahmad Nazrun Shuid
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate27%
Submission to final decision68 days
Acceptance to publication33 days
CiteScore2.900
Impact Factor1.813
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