Evidence-Based Complementary and Alternative Medicine

Network Pharmacology in Traditional Chinese Medicine


Publishing date
14 Mar 2014
Status
Published
Submission deadline
25 Oct 2013

Lead Editor

1Tsinghua University, Beijing, China

2University of Cambridge, Cambridge, UK

3Hong Kong Baptist University, Hong Kong

4The Second Military Medical University, Shanghai, China


Network Pharmacology in Traditional Chinese Medicine

Description

Network pharmacology is becoming a cutting-edge research field in current drug studies thanks to rapid progress in systems biology, network biology, and chemical biology. By integrating computational and experimental methods, network pharmacology is promising to be the next-generation mode of drug research. A remarkable feature of network pharmacology is the paradigm shift from “one drug, one target” to “multicomponent therapeutics, network target,” highlighting a holistic thinking also shared by traditional Chinese medicine (TCM). In TCM, the perspective of holism has long been central to herbal treatments on various diseases. Characterized by holistic theory and rich experience in multicomponent therapeutics, TCM herbal formulae offer bright prospects for the control of complex diseases in a systematic manner. Thus, introducing network pharmacology into TCM will provide novel methodologies and opportunities for discovering bioactive ingredients and endogenous/exogenous biomarkers, revealing mechanisms of action, and exploring scientific evidence of herbs and herbal formulae on the basis of complex biological systems.

We are delighted to announce a special issue of this journal on TCM network pharmacology. We invite authors to submit original research and review articles regarding the basic, clinical, and translational researches of TCM network pharmacology. Potential topics include, but are not limited to:

  • Methodologies of TCM network pharmacology:
    • Network-based target identification and action mechanism analyses for herbal ingredients
    • Bioinformatics, chemical biology, systems pharmacology, and systems biology methods in TCM network pharmacology
    • Network target theory and methods in TCM network pharmacology
  • Applications of network pharmacology in understanding traditional knowledge of herbal formulae:
    • Applications of network pharmacology in understanding herbal property, combinational rules of herbal formulae, as well as the relationship between herbal formulae and ZHENG (TCM syndrome)
  • Applications of TCM network pharmacology in herbal treatments:
    • Discovery of bioactive compounds and endogenous/exogenous biomarkers that are indicative of the bioefficacy of herbs and herbal formulae
    • Evidence of efficacy of herbs and herbal formulae
    • Elucidation of synergistic effects, toxicity, or side effects of herbs and herbal formulae
    • Elucidation of pharmacological or toxicological mechanism in herb-herb/herb-drug interactions

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ecam/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ecam/pharm/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 138460
  • - Editorial

Network Pharmacology in Traditional Chinese Medicine

Shao Li | Tai-Ping Fan | ... | Weidong Zhang
  • Special Issue
  • - Volume 2014
  • - Article ID 495840
  • - Research Article

A Network Pharmacology Approach to Determine Active Compounds and Action Mechanisms of Ge-Gen-Qin-Lian Decoction for Treatment of Type 2 Diabetes

Huiying Li | Linhua Zhao | ... | Xiaolin Tong
  • Special Issue
  • - Volume 2013
  • - Article ID 840427
  • - Research Article

dTGS: Method for Effective Components Identification from Traditional Chinese Medicine Formula and Mechanism Analysis

Ji Luo | Yinglong Ren | ... | Yun Wang
  • Special Issue
  • - Volume 2013
  • - Article ID 731370
  • - Research Article

A Module Analysis Approach to Investigate Molecular Mechanism of TCM Formula: A Trial on Shu-feng-jie-du Formula

Jianglong Song | Fangbo Zhang | ... | Hongjun Yang
  • Special Issue
  • - Volume 2013
  • - Article ID 352145
  • - Research Article

Study on Incompatibility of Traditional Chinese Medicine: Evidence from Formula Network, Chemical Space, and Metabolism Room

Wei Long | Xiao-Dong Zhang | ... | Sai-Jun Fan
  • Special Issue
  • - Volume 2013
  • - Article ID 245357
  • - Research Article

Bioinformatics Analysis for the Antirheumatic Effects of Huang-Lian-Jie-Du-Tang from a Network Perspective

Haiyang Fang | Yichuan Wang | ... | Jing Zhao
  • Special Issue
  • - Volume 2013
  • - Article ID 630723
  • - Research Article

Systemic Revealing Pharmacological Signalling Pathway Networks in the Hippocampus of Ischaemia-Reperfusion Mice Treated with Baicalin

Haixia Li | Yingying Zhang | ... | Jie Wang
  • Special Issue
  • - Volume 2013
  • - Article ID 901943
  • - Research Article

Network-Based Biomarkers for Cold Coagulation Blood Stasis Syndrome and the Therapeutic Effects of Shaofu Zhuyu Decoction in Rats

Shulan Su | Jinao Duan | ... | Yuping Tang
  • Special Issue
  • - Volume 2013
  • - Article ID 476749
  • - Erratum

Erratum to “Xiao-Xu-Ming Decoction Protects against Blood-Brain Barrier Disruption and Neurological Injury Induced by Cerebral Ischemia and Reperfusion in Rats”

Rui Lan | Jun Xiang | ... | Ding-Fang Cai
  • Special Issue
  • - Volume 2013
  • - Article ID 160168
  • - Research Article

Expression Profiling and Proteomic Analysis of JIN Chinese Herbal Formula in Lung Carcinoma H460 Xenografts

Luyu Zheng | Weiyi Zhang | ... | Xu Zhang
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate28%
Submission to final decision77 days
Acceptance to publication43 days
CiteScore2.010
Impact Factor1.984
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