Evidence-Based Complementary and Alternative Medicine

Natural Products for Ameliorating Degenerative Diseases


Status
Published

Lead Editor

1Ain-Shams University, Cairo, Egypt

2King Saud University, Riyadh, Saudi Arabia

3KLE University, Karnataka, India

4DY Patil University, Maharashtra, India


Natural Products for Ameliorating Degenerative Diseases

Description

Herbal medicines have been used for thousands of years for the treatment of several ailments. Herbal medicines contain different classes of secondary metabolites with beneficial health effects which are considered as important sources of lead structures. Recently, there has been a resurgence of interest in the use of natural products because of their reduced side effects compared to synthetic drugs. Several synthetic drugs have been used for the treatment of different degenerative diseases. However, some of these drugs are expensive and produce serious adverse effects. The use of these drugs may be unsuccessful in some cases due to development of tolerance and relapses and therefore may be of limited therapeutic benefits. In this regard, natural products represent an important source of new lead structures for the development of many drugs for ameliorating oxidative stress and degenerative diseases.

This special issue is dedicated to integrate the pharmacological mechanisms of natural products in ameliorating oxidative stress-associated diseases and the chemistry of secondary metabolites. We cordially invite researchers to contribute their original research articles and reviews in our special issue.

This comprises articles on the effect of natural products from plant, marine, and microbial sources (bacteria, algae, and fungi), herbal preparations, extracts, semisynthetic derivatives, and compounds modified by genetic/epigenetic techniques in the treatment of oxidative stress and degenerative diseases. Articles dealing with standardization/ isolation and structure identification of the active components which ameliorate these diseases are also included.

Potential topics include but are not limited to the following:

  • Molecular mechanisms of natural products against cancer, arthritis, and other degenerative diseases
  • Natural products in ameliorating neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases
  • Clinical and preclinical studies of natural products ameliorating degenerative diseases related to oxidative stress (such as hepatic, gastrointestinal, cardiovascular, and joint diseases)
  • Effect of natural products on degenerative and oxidative stress related diseases. Role of natural antioxidants in food and medicines
  • The use of nanoparticles and other drug delivery systems of natural products in ameliorating degenerative diseases
  • Bioavailability and pharmacokinetic studies of natural compounds used in ameliorating degenerative diseases
  • Standardized herbal preparations used in ameliorating degenerative diseases

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 3757403
  • - Editorial

Natural Products for Ameliorating Degenerative Diseases

Eman Al-Sayed | Indumathi Somasundaram | ... | Hanan Hagar
  • Special Issue
  • - Volume 2018
  • - Article ID 6254929
  • - Research Article

Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats

Md. Sakib Hossen | Md. Maruf Billah Prince | ... | Md. Ibrahim Khalil
  • Special Issue
  • - Volume 2018
  • - Article ID 8670421
  • - Research Article

A Chinese Herbal Preparation, Xiao-Er-An-Shen Decoction, Exerts Neuron Protection by Modulation of Differentiation and Antioxidant Activity in Cultured PC12 Cells

Zhonggui Li | Kelly Y. C. Lam | ... | Jianping Chen
  • Special Issue
  • - Volume 2018
  • - Article ID 5738101
  • - Research Article

Emodin Alleviates Liver Fibrosis of Mice by Reducing Infiltration of Gr1hi Monocytes

Xiang-An Zhao | Guangmei Chen | ... | Chao Wu
  • Special Issue
  • - Volume 2018
  • - Article ID 4360356
  • - Research Article

Hypoglycaemic and Antioxidant Effects of Propolis of Chihuahua in a Model of Experimental Diabetes

Nelly Rivera-Yañez | Mario Rodriguez-Canales | ... | M. A. Rodriguez-Monroy
  • Special Issue
  • - Volume 2018
  • - Article ID 9267653
  • - Research Article

Effect of Qingxin Kaiqiao Fang on Hippocampus mRNA Expression of the Inflammation-Related Genes IL-1β, GFAP, and Aβ in an Alzheimer’s Disease Rat Model

Dan-Dan Mao | Wen-Yu Yang | ... | Hai-Yan Hu
  • Special Issue
  • - Volume 2018
  • - Article ID 5382904
  • - Review Article

Genus Spondias: A Phytochemical and Pharmacological Review

Salma Sameh | Eman Al-Sayed | ... | Abdel Nasser Singab
  • Special Issue
  • - Volume 2017
  • - Article ID 4287890
  • - Research Article

Resveratrol Ameliorates Experimental Alcoholic Liver Disease by Modulating Oxidative Stress

He Peiyuan | Hou Zhiping | ... | Mustapha Umar Imam
  • Special Issue
  • - Volume 2017
  • - Article ID 8085325
  • - Research Article

Icariin Regulates the Bidirectional Differentiation of Bone Marrow Mesenchymal Stem Cells through Canonical Wnt Signaling Pathway

Jun-ming Huang | Yuan Bao | ... | Feng-jin Guo
  • Special Issue
  • - Volume 2017
  • - Article ID 7829059
  • - Research Article

Lannea acida A. Rich. (Anacardiaceae) Ethanol Extract Exhibits Estrogenic Effects and Prevents Bone Loss in an Ovariectomized Rat Model of Osteoporosis

Mouchili Riepouo Oumarou | Stéphane Zingue | ... | Dieudonné Njamen
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate28%
Submission to final decision72 days
Acceptance to publication43 days
CiteScore2.010
Impact Factor1.984
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