Evidence-Based Complementary and Alternative Medicine

Looking for New Herbal Treatments for Metabolic Syndrome


Status
Published

Lead Editor

1Kyung Hee University, Seoul, Republic of Korea

2Johns Hopkins University, Baltimore, USA

3Korea Kyung Hee University, Baku, Azerbaijan


Looking for New Herbal Treatments for Metabolic Syndrome

Description

Metabolic syndrome is a disorder of energy utilization and storage, diagnosed by a cooccurrence of abdominal central obesity, elevated blood pressure, elevated fasting plasma glucose, and high serum triglycerides. The principal symptom of metabolic syndrome is central obesity, overweight with adipose tissue accumulation. Other signs of metabolic syndrome include high blood pressure, decreased fasting serum HDL cholesterol, elevated fasting serum triglyceride level, impaired fasting glucose, insulin resistance, or prediabetes. Associated conditions include hyperuricemia, fatty liver, especially in concurrent obesity, progressing to nonalcoholic fatty liver disease (NAFLD), and polycystic ovarian syndrome in women.

There is an increasing interest and popularity of herbal medicine worldwide, which is accompanied by increasing concerns about its effectiveness and potential toxicity. Several ingredients, such as polyphenolic compounds berberine, flavonoids, and curcumin, have been studied extensively by using various animal models. The targeting of mechanism by these agents remains primary focus for several diseases including diabetes, obesity, NAFLD, cardiovascular, respiratory, neurodegenerative, and gastrointestinal diseases, and cancer. The experimental evidence especially demonstrating the lipid-lowering effect of herbal medicine and ingredients in cell culture and animal models is needed, and the strengths, shortcomings of experimental designs, and clinical applicability in these studies are required.

Investigators are invited to submit original research as well as review articles which explore pharmacological and molecular mechanism of herbal medicines or derived phytochemicals and natural products targeting specific mechanism in the management of metabolic syndrome.

Potential topics include, but are not limited to:

  • Elucidation of mechanism of phytochemicals, herbal medicines, and natural products based on pharmacological challenge of agonist or antagonist or receptor expression studies
  • Bioanalytical studies to reveal herbal medicines as mechanism modulators
  • Biochip and omics study of herbal medicines and natural products
  • Synergistic or additive actions of herbal medicines, phytochemicals, or natural products targeting mechanism
  • Development of multifunctional and polypharmacological phytochemicals, herbal medicines, and natural products targeting mechanism
  • Development of design, receptor targeting, and acupuncture

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 7198490
  • - Editorial

Looking for New Herbal Treatments for Metabolic Syndrome

Hyeung-Jin Jang | Jae-Young Um | ... | Won-Seok Chung
  • Special Issue
  • - Volume 2016
  • - Article ID 8674397
  • - Research Article

Veratri Nigri Rhizoma et Radix (Veratrum nigrum L.) and Its Constituent Jervine Prevent Adipogenesis via Activation of the LKB1-AMPKα-ACC Axis In Vivo and In Vitro

Jinbong Park | Yong-Deok Jeon | ... | Jae-Young Um
  • Special Issue
  • - Volume 2016
  • - Article ID 6828514
  • - Research Article

Antihyperglycemic and Antiobesity Effects of JAL2 on db/db Mice

In-Seung Lee | Ki-Suk Kim | ... | Hyeung-Jin Jang
  • Special Issue
  • - Volume 2016
  • - Article ID 9417362
  • - Research Article

The Preventive Effect of Zuogui Wan on Offspring Rats’ Impaired Glucose Tolerance Whose Mothers Had Gestational Diabetes Mellitus

Yuwei Wang | Qianjin Feng | ... | Shuangrong Gao
  • Special Issue
  • - Volume 2015
  • - Article ID 171742
  • - Review Article

Medicinal Plants Qua Glucagon-Like Peptide-1 Secretagogue via Intestinal Nutrient Sensors

Ki-Suk Kim | Hyeung-Jin Jang
  • Special Issue
  • - Volume 2015
  • - Article ID 474032
  • - Research Article

The Combination of Resveratrol and Quercetin Attenuates Metabolic Syndrome in Rats by Modifying the Serum Fatty Acid Composition and by Upregulating SIRT 1 and SIRT 2 Expression in White Adipose Tissue

Ana Elena Peredo-Escárcega | Verónica Guarner-Lans | ... | María Esther Rubio-Ruiz
  • Special Issue
  • - Volume 2015
  • - Article ID 352647
  • - Research Article

ACE Reduces Metabolic Abnormalities in a High-Fat Diet Mouse Model

Seong-Jong Lee | Jong-Min Han | ... | In-Chan Seol
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate27%
Submission to final decision68 days
Acceptance to publication33 days
CiteScore2.900
Impact Factor1.813
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