Accuracy of D-Dimers to Rule Out Venous Thromboembolism Events across Age Categories

Table 1

Performance of the D-dimers “Vidas” assay according to age categories in 1,004 patients with suspected venous thromboembolic events (VTE). 95%CI: 95% confidence interval.

Age categories (years)	No. of patients	No. of VTE	Sensitivity [95%CI]	Specificity [95%CI]	Negative predictive value [95%CI]
<30	91	5	80% [28.4–99.5]	83.5% [74.3–90.5]	98.7% [93.0–100]
30–39	121	5	80% [28.4–99.5]	75.6% [67.0–83.0]	98.9% [94.0–100]
40–49	151	7	100% [59.0–100]	78.7% [71.3–84.9]	100% [96.9–100]
50–59	155	6	83.3% [35.9–99.6]	69.2% [61.4–76.4]	99.1% [95.0–100]
60–69	142	11	100% [71.5–100]	56% [47.1–64.5]	100% [95.2–100]
70–79	165	14	100% [76.8–100]	33.3% [26.1–41.1]	100% [93.4–100]
80–89	134	18	100% [81.5–100]	10.1% [5.3–17.0]	100% [73.5–100]
>90	45	4	100% [39.8–100]	7.3% [4.0–20.0]	100% [29.2–100]
All patients	1,004	70	95.8% [88.0–99.0]	57.4% [54.2–60.5]	99.4% [98.4–99.9]