Table of Contents Author Guidelines Submit a Manuscript
Emergency Medicine International
Volume 2014, Article ID 638102, 5 pages
http://dx.doi.org/10.1155/2014/638102
Clinical Study

The Efficacy of Nebulized Furosemide and Salbutamol Compared with Salbutamol Alone in Reactive Airway Disease: A Double Blind Randomized, Clinical Trial

1Department of Emergency Medicine, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6193673166, Iran
2Department of Internal Medicine, Division of Pulmonology, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6193673166, Iran

Received 4 December 2013; Revised 8 February 2014; Accepted 3 March 2014; Published 27 April 2014

Academic Editor: Jeffrey R. Avner

Copyright © 2014 Kambiz Masoumi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. B. Parshall, R. M. Schwartzstein, L. Adams et al., “An official American thoracic society statement: update on the mechanisms, assessment, and management of dyspnea,” The American Journal of Respiratory and Critical Care Medicine, vol. 185, no. 4, pp. 435–452, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. D. A. Mahler, “Dyspnea: diagnosis and management,” Clinics in Chest Medicine, vol. 8, no. 2, pp. 215–230, 1987. View at Google Scholar · View at Scopus
  3. C. D. Mulrow, C. R. Lucey, and L. E. Farnett, “Discriminating causes of dyspnea through clinical examination,” Journal of General Internal Medicine, vol. 8, no. 7, pp. 383–392, 1993. View at Google Scholar · View at Scopus
  4. J. V. Fahy and P. M. O'Byrne, “‘Reactive airways disease’: a lazy term of uncertain meaning that should be abandoned,” The American Journal of Respiratory and Critical Care Medicine, vol. 163, no. 4, pp. 822–823, 2001. View at Google Scholar · View at Scopus
  5. M. Weinberger, M. D. Murray, D. G. Marrero et al., “Effectiveness of pharmacist care for patients with reactive airways disease: a randomized controlled trial,” Journal of the American Medical Association, vol. 288, no. 13, pp. 1594–1602, 2002. View at Google Scholar · View at Scopus
  6. S. R. Salpeter, T. M. Ormiston, and E. E. Salpeter, “Cardioselective β-blockers in patients with reactive airway disease: a meta-analysis,” Annals of Internal Medicine, vol. 137, no. 9, pp. 715–725, 2002. View at Google Scholar · View at Scopus
  7. G. C. Moudgil, “The patient with reactive airways disease,” Canadian Journal of Anesthesia, vol. 44, pp. R77–R89, 1997. View at Google Scholar
  8. W. M. Tierney, M. D. Murray, D. L. Gaskins, and X.-H. Zhou, “Using computer-based medical records to predict mortality risk for inner-city patients with reactive airways disease,” Journal of the American Medical Informatics Association, vol. 4, no. 4, pp. 313–321, 1997. View at Google Scholar · View at Scopus
  9. S. M. Brooks, M. A. Weiss, and I. L. Bernstein, “Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposures,” Chest, vol. 88, no. 3, pp. 376–384, 1985. View at Google Scholar · View at Scopus
  10. M. B. Shirk, K. R. Donahue, and J. Shirvani, “Unlabeled uses of nebulized medications,” The American Journal of Health-System Pharmacy, vol. 63, no. 18, pp. 1704–1716, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. D. Hess, D. Fisher, P. Williams, S. Pooler, and R. M. Kacmarek, “Medication nebulizer performance: effects of diluent volume, nebulizer flow, and nebulizer brand,” Chest, vol. 110, no. 2, pp. 498–505, 1996. View at Google Scholar · View at Scopus
  12. J. P. Karpel, F. Dworkin, D. Hager et al., “Inhaled furosemide is not effective in acute asthma,” Chest, vol. 106, no. 5, pp. 1396–1400, 1994. View at Google Scholar · View at Scopus
  13. N. Shimoyama and M. Shimoyama, “Nebulized furosemide as a novel treatment for dyspnea in terminal cancer patients,” Journal of Pain and Symptom Management, vol. 23, no. 1, pp. 73–76, 2002. View at Publisher · View at Google Scholar · View at Scopus
  14. S. Bianco, M. G. Pieroni, R. M. Refini, M. Robuschi, A. Vaghi, and P. Sestini, “Inhaled loop diuretics as potential new anti-asthmatic drugs,” European Respiratory Journal, vol. 6, no. 1, pp. 130–134, 1993. View at Google Scholar · View at Scopus
  15. H. Kohara, H. Ueoka, K. Aoe et al., “Effect of nebulized furosemide in terminally ill cancer patients with dyspnea,” Journal of Pain and Symptom Management, vol. 26, no. 4, pp. 962–967, 2003. View at Publisher · View at Google Scholar · View at Scopus
  16. T. Nishino, T. Ide, T. Sudo, and J. Sato, “Inhaled furosemide greatly alleviates the sensation of experimentally induced dyspnea,” The American Journal of Respiratory and Critical Care Medicine, vol. 161, no. 6, pp. 1963–1967, 2000. View at Google Scholar · View at Scopus
  17. Z. S. Yen and S. C. Chen, “Nebulised furosemide in acute adult asthma,” Emergency Medicine Journal, vol. 22, no. 9, pp. 654–655, 2005. View at Publisher · View at Google Scholar · View at Scopus
  18. Y. Ono, T. Kondo, T. Tanigaki, and Y. Ohta, “Furosemide given by inhalation ameliorates acute exacerbation of asthma,” Journal of Asthma, vol. 34, no. 4, pp. 283–289, 1997. View at Google Scholar · View at Scopus
  19. J. C. Pendino, L. J. Nannini, K. R. Chapman, A. Slutsky, and N. A. Molfino, “Effect of inhaled furosemide in acute asthma,” Journal of Asthma, vol. 35, no. 1, pp. 89–93, 1998. View at Google Scholar · View at Scopus
  20. S. Bianco, M. Robuschi, A. Vaghi, and M. Pasargiklian, “Prevention of exercise-induced bronchoconstriction by inhaled frusemide,” The Lancet, vol. 2, no. 8605, pp. 252–255, 1988. View at Google Scholar · View at Scopus
  21. T. Chin, L. Franchi, and E. Nussbaum, “Reversal of bronchial obstruction in children with mild stable asthma by aerosolized furosemide,” Pediatric pulmonology, vol. 18, no. 2, pp. 93–98, 1994. View at Google Scholar · View at Scopus
  22. D. H. Yates, B. J. O'Connor, G. Yilmaz et al., “Effect of acute and chronic inhaled furosemide on bronchial hyperresponsiveness in mild asthma,” The American Journal of Respiratory and Critical Care Medicine, vol. 152, no. 6 I, pp. 2173–2175, 1995. View at Google Scholar · View at Scopus
  23. J. C. Rodríguez Vázquez, P. P. Pino Alfonso, C. Gassiot Nuño, and I. Páez Prats, “Usefulness of inhaled furosemide in a bronchial asthma attack,” Journal of Investigational Allergology and Clinical Immunology, vol. 8, no. 5, pp. 290–293, 1998. View at Google Scholar · View at Scopus
  24. S. Bianco, M. G. Pieroni, R. M. Refini, L. Rottoli, and P. Sestini, “Protective effect of inhaled furosemide on allergen-induced early and late asthmatic reactions,” The New England Journal of Medicine, vol. 321, no. 16, pp. 1069–1073, 1989. View at Google Scholar · View at Scopus