Research Article

Validation of EGSYS Score in Prediction of Cardiogenic Syncope

Table 2

Frequency of EGSYS risk factors in the studied patients.

Risk factorsNumber (%)OR3 (95% CI4) valueScore#

EGSYS-U1
 Abnormal ECG/cardiopathy134 (67.3)11.27 (5.42–23.01)<0.001
 Palpitations/dyspnea59 (30.1)7.48 (3.3–16.96)<0.001
 Syncope in supine position/effort syncope68 (34.2)1.37 (0.74–2.40)0.315
 Age >64 years87 (45.1)4.54 (2.24–8.53)<0.001
 No precipitating and predisposing factors128 (65.6)0.84 (0.46–1.53)0.576
 No prodromes46 (23.6)3.84 (1.73–8.52)0.001
 Blurred vision40 (20.7)5.12 (2.37–11.06)<0.001
 Neurovegetative signs during recovery phase68 (35.2)2.19 (1.20–4.01)0.010
 Precipitating and predisposing factors67 (34.4)0.84 (0.46–1.53)0.575
 Autonomic prodromes67 (34.2)0.13 (0.02–1.05)0.055
EGSYS–M2
 Abnormal ECG/cardiopathy134 (67.3)11.27 (5.42–23.01)<0.001
 Palpitations/dyspnea59 (30.1)7.48 (3.3–16.96)<0.001
 Effort syncope51 (26.4)0.94 (0.49–1.79)0.844
 Syncope in supine position9 (9.8)4.28 (1.20–15.25)0.016
 Autonomic prodromes67 (34.2)0.13 (0.02–1.05)0.025
 Precipitating and predisposing factors67 (34.4)0.84 (0.46–1.53)0.575

Presence of one or more ECG abnormality listed in Definitions.
Defined in Methods.
Defined in Methods.
#Total score ≥3 indicates patients at risk for presence of cardiac cause.
1EGSYS-U: Evaluation of Guidelines in Syncope Study-Univariate.
2EGSYS-M: Evaluation of Guidelines in Syncope Study-Multivariate.
3OR: odds ratio.
4CI: confidence interval.