Research Article

Presentations Related to Acute Paracetamol Intoxication in an Urban Emergency Department in Switzerland

Table 1

Main characteristics of cases presenting due to paracetamol intoxication.

All (N = 181)Intentional (n = 143)Unintentional (n = 38)

Age in years25.0 (16–85)23.0 (16–85)43.5 (16–79)<0.001
Women138 (76)121 (85)17 (45)<0.001
Swiss citizens147 (81)119 (83)28 (74)0.18
Paracetamol g/24 h10.8 (5–90)12.9 (5–90)8.2 (5–25)<0.001
Intake as a single dose120 (66)115 (80)5 (13)<0.001
<24 h between ingestion and presentation131(72)120 (84)11 (29)<0.001
Intake of paracetamol only99 (55)71 (50)28 (74)0.008
Psychiatric comorbidities142 (78)133 (93)9 (24)<0.001
DILI8 (4)7 (5)1 (3)0.54
ALF15 (8)6 (4)9 (24)<0.001
Death2 (1)1 (<1)1 (3)0.30
Treatment as outpatients84 (46)75 (52)9 (24)0.002
Time of hospitalisation in days£2.0 (1–21)2.0 (1–21)2.0 (1–15)0.001

£Time of hospitalisation not known in ten cases with admission to another hospital. Values are expressed as median (range) or n (%); bold numbers indicate significant differences () between the intentional and unintentional groups.