Research Article

Contribution of Experimental Animal Research Studies to the Emergency Medicine Literature

Table 3

Characteristics of the experimental studies subjected in the publications.

ā€‰VariablesNumber of studies (%)

Department of the First AuthorEmergency Medicine190 (28.8)
Anesthesiology and Critical Care107 (16.2)
Orthopedics and Traumatology72 (10.9)
Surgery64 (9.7)
Preclinical Sciences37 (5.6)
Pediatrics28 (4.2)
Neurosurgery26 (4)
Burn, Plastic and Reconstructive Surgery24 (3.7)
Cardiovascular21 (3.2)
Biomechanical or Biomedical Engineering13 (2)
Cardiothoracic Surgery7 (1)
Experimental Surgery and Research7 (1)
Pathology7 (1)
Others58 (8.8)

Subject SpeciesRodent367 (49.9)
Swine272 (37)
Rabbit52 (7.1)
Sheep20 (2.7)
Dog13 (1.8)
Others12 (1.5)

Experimental ModelCardiac Arrest257 (34.9)
Inflammation/Infection/Ischemia/Trauma of Major Organs87 (11.8)
Hemorrhage/Hemorrhagic Shock/Coagulation81 (11)
Bone Defects/Fracture Healing66 (9)
Burn Injury30 (4.1)
Spinal Cord Injury26 (3.5)
Ischemia/Reperfusion23 (3.1)
Intoxication/Poisoning23 (3.1)
Peripheral Nerve Injury22 (3)
Therapeutic Hypothermia17 (2.3)
Wound Healing16 (2.2)
Sepsis15 (2)
Cerebral Ischemia14 (1.9)
Traumatic Brain Injury13 (1.8)
Technique-Training12 (1.6)
Muscle/Tendon/Ligament Injury11 (1.5)
Others23 (3.1)

Target Organ/System EvaluatedBrain101 (13.7)
Hemodynamic Parameters94 (12.8)
Heart80 (10.9)
Bones61 (8.3)
Lungs51 (6.9)
Spinal Cord26 (3.5)
Peripheral Nerves23 (3.1)
Skin21 (2.9)
Coagulation System20 (2.7)
Kidneys17 (2.3)
Musculoskeletal System17 (2.3)
Intestines9 (1.2)
Liver8 (1.1)
Multiple Organs23 (3.1)
Others185 (25.1)

Type of the Evaluation MethodOutcome/survival408 (55.4)
Histopathological354 (48.1)
Blood/serum124 (16.8)
Radiologic36 (4.9)
Polymerase Chain Reaction25 (3.4)
Electrophysiologic12 (1.6)