Research Article
The Impact of EGDT on Sepsis Mortality in a Single Tertiary Care Center in Lebanon
| | | Protocol N= 145 | Control N= 145 | p-value |
| | Continuous mean ± SD | | | |
| | Age (years) | 71.9 ± 14.1 | 72.9 ± 16.3 | 0.573 |
| | Categorical no.() | | | |
| | Male | 75 (51.7) | 76 (52.4) | 0.906 |
| | Diagnosis | | | 0.280 | | Septic shock | 92 (63.4) | 83 (57.2) | | Severe sepsis | 53 (36.6) | 62 (42.8) |
| | HTN | 102 (70.3) | 101 (69.7) | 0.898 |
| | DM | 71(49.0) | 68 (46.9) | 0.724 |
| | CAD | 64 (44.1) | 59 (40.7) | 0.552 |
| | Systolic CHF: EF<40 | 32 (22.1) | 29 (20.0) | 0.666 |
| | COPD/Emphysema | 13 (9.0) | 19 (13.1) | 0.261 |
| | CKD on HD | 4 (2.8) | 5 (3.4) | 0.735 |
| | CVA | 19 (13.1) | 20 (13.8) | 0.863 |
| | Site of Infection | | | <0.001∗ | | Lung | 61 (42.1) | 45 (31.0) | | Gastrointestinal | 21 (14.5) | 11 (7.6) | | Urine | 52 (35.9) | 49 (33.8) | | Skin | 6 (4.1) | 19 (13.1) | | Bile | 0 (0.0) | 5 (3.4) | | Liver | 0 (0.0) | 1 (0.7) | | Undetermined | 5 (3.4) | 15 (10.3) |
| | Microbiology Isolate | | | |
| | CoNS1 | 1 (0.7) | 2 (2.1) | 0.562 |
| | Staphylococcus aureus | 6 (4.1) | 3 (2.1) | 0.310 |
| | Escherichia coli | 44 (37.9) | 61 (42.1) | 0.472 |
| | klebsiella pneumonia | 9 (6.2) | 11 (7.6) | 0.643 |
| | pseudomonas aeroginosa | 12 (8.3) | 7 (4.8) | 0.235 |
| | Acinetobacter baumani | 8 (5.5) | 5 (3.4) | 0.395 |
| | Enterococcus spp. | 2 (1.4) | 9 (6.3) | 0.030∗ |
| | Proteus mirabillis | 4 (2.8) | 7 (4.8) | 0.356 |
| | Streptococcus spp. | 9 (6.2) | 6 (4.1) | 0.426 |
| | Clostridium spp. | 3 (2.1) | 1 (0.7) | 0.314 |
| | Others2 | 3 (2.1) | 0 (0.0) | 0.281 |
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-negative staphylococci. 2Others included: Bacteroides fragilis, Candida albicans, Citrobacter, Diphteroids spp., Enterobacter cloacae, Haemophilus influenzae (type B), Haemophilus parainfluenzae, Legionella pneumophila, Leuconostoc , Morganella morgani, Peptococcus spp., Providncia stuartii, Serratia marsescens, and Stenotrophomonas maltophilia. ∗p=<0.05 considered significant. |
