Research Article
The Impact of EGDT on Sepsis Mortality in a Single Tertiary Care Center in Lebanon
Table 3
Resuscitation parameters.
| | | Protocol N= 145 | Control N= 145 | p-value |
| | Vital signs after 6 hours |
| | Continuous mean ± SD | |
| | SBP (mmHg) | 103.3 ± 19.9 | 104.7 ± 18.9 | 0.595 |
| | DBP (mmHg) | 57.2 ± 13.0 | 59.1 ± 14.5 | 0.243 |
| | MAP (mmHg) | 69.8 ± 13.8 | 73.9 ± 14.9 | 0.022∗ |
| | HR (bpm) | 92.4 ± 21.0 | 91.9 ± 20.0 | 00.834 |
| | O2 Saturation () | 96.0 ± 11.2 | 97.1 ± 6.8 | 0.394 |
| | Temperature (°C) | 37.3 ± 0.9 | 37.4 ± 5.9 | 0.781 |
| | RR (breath/min) | 21.8 ± 5.5 | 21.0 ± 4.3 | 0.166 |
| | Resources variables |
| | Continuous mean ± SD | |
| | IV fluid requirements at first 6 hrs (L) | 3.8 ± 1.7 | 2.7 ± 2.0 | <0.001∗ |
| | IV fluid requirements at first 24 hrs (L) | 6.1 ± 2.1 | 4.9 ± 2.8 | <0.001∗ |
| | Time to initiation of antibiotics (hrs) | 2.0 ± 3.6 | 2.8 ± 2.6 | 0.054 |
| | Time to vasopressor/inotrope use within the 1st 24hrs (hrs) | 9.1 ± 22.6 | 7.7 ± 7.0 | 0.67 |
| | Duration of vasopressor/inotrope treatment within 1st 24hrs (hrs) | 50.9 ± 649.6 | 40.0 ± 56.1 | 0.234 |
| | Categorical No () | |
| | Vasopressor/inotrope use within 1st 24hrs | 88 (60.6) | 52 (35.8) | <0.001∗ |
| | CVC placement | 29 (21.2) | 14 (9.9) | 0.010∗ |
| | Mechanical ventilation | 31 (21.5) | 23 (15.9) | 0.217 |
| | Steroid use | 50 (34.5) | 54 (37.2) | 0.624 |
| | Antibiotic use | 143 (98.6) | 145 (100.0) | 0.155 |
| | Appropriate antibiotic use1 | 91 (97.8)% | 75 (91.5) | 0.056 |
| | Antibiotics initiation in the ED | 136 (93.8) | 144 (99.3) | 0.010∗ |
| | Antibiotics initiation in the ICU | 4 (2.8) | 1 (0.7) | 0.176 |
| | Antibiotics initiation in the GPU | 3 (2.1) | 0 (0) | 0.082 |
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use of antibiotics was defined as preliminary antibiotic given in the first 48hrs of treatment covering the bacteria grown later in bacteriology. |
