The Association of Extreme Tachycardia and Sustained Return of Spontaneous Circulation after Nontraumatic Out-of-Hospital Cardiac Arrest

Table 2

Multivariable logistic regression analysis for the outcomes.

	Sustained ROSC			One-month survival				Six-month good neurologic outcome
	OR	(95% CI)			OR	(95% CI)			OR	(95% CI)
Heart rate group
Bradycardia	0.79	(0.23–2.75)	0.711		1.92	(0.41–9.10)	0.411		1.69	(0.29–9.82)	0.558
Normal HR	1.00	(Reference)			1.00	(Reference)			1.00	(Reference)
Tachycardia	1.23	(0.54–2.82)	0.624		0.70	(0.27–1.79)	0.449		0.79	(0.29–2.16)	0.642
Extreme tachycardia	11.30	(1.35–94.53)	0.025^∗		0.82	(0.27–2.49)	0.724		0.92	(0.28–3.08)	0.896
Age, per 10 years	0.85	(0.66–1.11)	0.230		0.82	(0.66–1.02)	0.079		0.80	(0.63–1.02)	0.073
Male	0.73	(0.34–1.57)	0.427		2.15	(1.02–4.55)	0.045^∗		3.45	(1.56–21.50)	0.009
Witnessed arrest	2.15	(0.91–5.11)	0.083		1.30	(0.49–3.46)	0.605		0.96	(0.34–2.65)	0.929
Public place	1.84	(0.56–6.02)	0.313		1.11	(0.42–2.96)	0.829		1.83	(0.66–5.07)	0.245
Shockable initial rhythm	1.19	(0.37–3.84)	0.268		3.03	(1.22–7.51)	0.017^∗		3.18	(1.25–8.10)	0.015
Bystander CPR	1.67	(0.67–4.16)	0.268		1.81	(0.76–4.34)	0.182		1.87	(0.71–4.91)	0.205
Total epinephrine dose, per 1 mg	0.89	(0.75–1.05)	0.152		0.69	(0.52–0.92)	0.011		0.77	(0.57–1.04)	0.083
MAP ≥ 80 mmHg at ROSC	0.90	(0.43–1.88)	0.778		2.21	(0.98–4.97)	0.056		1.84	(0.76–4.43)	0.175
No-flow time, per 1 min	1.02	(0.98–1.06)	0.395		0.95	(0.91–1.00)	0.057		0.94	(0.89–0.99)	0.042^∗
Low-flow time, per 1 min	0.99	(0.97–1.02)	0.716		0.95	(0.91–0.98)	0.005^∗		0.94	(0.91–0.98)	0.007^∗

Bradycardia, HR < 60 beats/min; normal, 60 ≤ HR ≤ 100 beats/min; tachycardia, 100 < HR < 150 beats/min; extreme tachycardia, HR ≥ 150 beats/min. ROSC, return of spontaneous circulation; OR, odds ratio; CI, confidence interval; HR, heart rate; CPR, cardiopulmonary resuscitation; MAP, mean arterial pressure. Statistically significant.