Comparison of Dopamine and Norepinephrine Use for the Treatment of Hypotension in Out-Of-Hospital Cardiac Arrest Patients with Return of Spontaneous Circulation
Table 1
Characteristics of patients treated with different inotropic agents after return of spontaneous circulation.
Dopamine (n = 670)
Norepinephrine (n = 92)
Dopamine + Norepinephrine (n = 249)
-value
Age
68.7 ± 15.87
66.4 ± 18.02
68.1 ± 16.26
0.438
Male
367 (54.8%)
52 (56.5%)
138 (55.4%)
0.989
Comobility
Heart failure
92 (13.7%)
10 (10.9%)
26 (10.4%)
0.355
CVA
136 (20.3%)
25 (27.2%)
53 (21.3%)
0.318
COPD
165 (24.6%)
16 (17.4%)
47 (18.9%)
0.083
DM
194 (29.0%)
32 (34.8%)
84 (33.7%)
0.252
Renal disease
131 (19.6%)
11 (12.0%)
33 (13.3%)
0.029
Liver cirrhosis
85 (12.7%)
11 (12.0%)
30 (12.0%)
0.955
Malignancy
89 (13.3%)
13 (14.1%)
40 (16.1%)
0.559
CCI
3 ± 1.5
2 ± 2.0
3 ± 1.5
0.574
Status upon arrival
EMT transfer
482 (71.9%)
73 (79.3%)
178 (71.5%)
0.302
Shockable rhythm
71 (10.6%)
14 (15.2%)
21 (8.4%)
0.190
Treatment in ED
Epinephrine (mg)
5 ± 2.5
5 ± 2.0
7 ± 3.5
<0.001
Sodium bicarbonate (vial)
4 ± 4.0
4 ± 4.5
8 ± 5.0
<0.001
PCI
28 (4.2%)
4 (4.3%)
5 (2.0%)
0.278
ECMO
7 (1.0%)
2 (2.2%)
1 (0.4%)
0.330
ICU admission
475 (70.9%)
66 (71.7%)
146 (58.6%)
0.001
CVA: cerebrovascular accident; COPD: chronic obstruction pulmonary disease; DM: diabetes mellitus; EMT: emergency medical technician; shockable rhythm: ventricular fibrillation and pulseless ventricular tachycardia; ED: emergency department; PCI: percutaneous coronary intervention; ECMO: extracorporeal membrane oxygenation; ICU: intensive care unit.
