Research Article
Comparing Mortality Risk Predictive Ability of Different Scoring Systems in Cirrhotic Patients with Bacteremia
Table 2
Microbiological distribution, infection source, sepsis severity, and antimicrobial agent administration of cirrhotic patients with bacteremia (n = 127).
| Characteristics | All (n = 127) | Nonsurvivors (n = 41) | Survivors (n = 86) | value |
| SIRS, n (%) | 93 (73.2) | 32 (78.0) | 61 (70.9) | 0.52 |
| qSOFA score, n (%) | | <2 | 86 (67.7) | 20 (48.8) | 66 (76.7) | | ≥2 | 41 (32.3) | 21 (51.2) | 20 (23.3) | |
| Pitt bacteremia score, n (%) | | <4 | 107 (84.3) | 27 (65.9) | 80 (93.0) | | ≥4 | 20 (15.7) | 14 (34.1) | 6 (7.0) | |
| ACLF, n (%) | 52 (40.9) | 28 (68.3) | 24 (27.9) | |
| Number of organ failures, n (%) | | 0 | 45 (35.4) | 3 (7.3) | 42 (48.8) | | 1 | 33 (26.0) | 7 (17.0) | 26 (30.2) | | 2 | 38 (29.9) | 20 (48.8) | 18 (20.9) | | ≥3 | 11 (8.7) | 11 (26.8) | 0 (0) | |
| CLIF-C OF score, mean ± SD | 9 ± 2 | 11 ± 2 | 8 ± 1 | |
| Infection source, n (%) | Respiratory tract infection | 8 (6.3) | 4 (9.8) | 4 (4.7) | 0.27 | Urinary tract infection | 17 (13.4) | 2 (4.9) | 15 (17.4) | 0.06 | Spontaneous bacterial peritonitis | 44 (34.6) | 19 (46.3) | 25 (29.1) | 0.07 | Biliary tract infection | 27 (21.3) | 10 (24.4) | 17 (19.8) | 0.64 | Soft tissue infection | 21 (16.5) | 6 (14.6) | 15 (17.4) | 0.80 | Primary bacteremia | 10 (7.9) | 0 (0) | 10 (11.6) | |
| Microbiological distribution, n (%) | Gram-positive pathogen | 44 (34.6) | 13 (31.7) | 31 (36.0) | 0.69 | Staphylococcus aureus | 14 (11.0) | 6 (14.6) | 8 (9.3) | | Streptococcus pneumoniae | 14 (11.0) | 4 (9.8) | 10 (11.6) | | Viridans Streptococcus | 5 (3.9) | 1 (2.4) | 4 (4.7) | | Others | 11 (8.7) | 2 (4.9) | 9 (10.5) | |
| Gram-negative pathogen | 73 (57.5) | 27 (65.9) | 46 (53.5) | 0.25 | Escherichia coli | 27 (21.3) | 11 (26.8) | 16 (18.6) | | Klebsiella pneumoniae | 19 (15.0) | 5 (12.2) | 14 (16.3) | | Pseudomonas aeruginosa | 8 (6.3) | 4 (9.8) | 4 (4.7) | | Others | 19 (15.0) | 7 (17.0) | 12 (14.0) | |
| Polymicrobial | 10 (7.9) | 1 (2.4) | 9 (10.5) | 0.17 |
| Antimicrobial appropriateness, n (%) | 92 (72.4) | 27 (65.9) | 65 (75.6) | 0.65 |
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SIRS: systemic inflammatory response syndrome. qSOFA: quick sequential organ failure assessment. ACLF: acute-on-chronic liver failure. CLIF-C OF: chronic liver failure consortium organ failure score. |