Research Article

Comparing Mortality Risk Predictive Ability of Different Scoring Systems in Cirrhotic Patients with Bacteremia

Table 2

Microbiological distribution, infection source, sepsis severity, and antimicrobial agent administration of cirrhotic patients with bacteremia (n = 127).

CharacteristicsAll (n = 127)Nonsurvivors (n = 41)Survivors (n = 86) value

SIRS, n (%)93 (73.2)32 (78.0)61 (70.9)0.52

qSOFA score, n (%)
 <286 (67.7)20 (48.8)66 (76.7)
 ≥241 (32.3)21 (51.2)20 (23.3)

Pitt bacteremia score, n (%)
 <4107 (84.3)27 (65.9)80 (93.0)
 ≥420 (15.7)14 (34.1)6 (7.0)

ACLF, n (%)52 (40.9)28 (68.3)24 (27.9)

Number of organ failures, n (%)
 045 (35.4)3 (7.3)42 (48.8)
 133 (26.0)7 (17.0)26 (30.2)
 238 (29.9)20 (48.8)18 (20.9)
 ≥311 (8.7)11 (26.8)0 (0)

CLIF-C OF score, mean ± SD9 ± 211 ± 28 ± 1

Infection source, n (%)
 Respiratory tract infection8 (6.3)4 (9.8)4 (4.7)0.27
 Urinary tract infection17 (13.4)2 (4.9)15 (17.4)0.06
 Spontaneous bacterial peritonitis44 (34.6)19 (46.3)25 (29.1)0.07
 Biliary tract infection27 (21.3)10 (24.4)17 (19.8)0.64
 Soft tissue infection21 (16.5)6 (14.6)15 (17.4)0.80
 Primary bacteremia10 (7.9)0 (0)10 (11.6)

Microbiological distribution, n (%)
Gram-positive pathogen44 (34.6)13 (31.7)31 (36.0)0.69
Staphylococcus aureus14 (11.0)6 (14.6)8 (9.3)
Streptococcus pneumoniae14 (11.0)4 (9.8)10 (11.6)
 Viridans Streptococcus5 (3.9)1 (2.4)4 (4.7)
 Others11 (8.7)2 (4.9)9 (10.5)

Gram-negative pathogen73 (57.5)27 (65.9)46 (53.5)0.25
Escherichia coli27 (21.3)11 (26.8)16 (18.6)
Klebsiella pneumoniae19 (15.0)5 (12.2)14 (16.3)
Pseudomonas aeruginosa8 (6.3)4 (9.8)4 (4.7)
 Others19 (15.0)7 (17.0)12 (14.0)

Polymicrobial10 (7.9)1 (2.4)9 (10.5)0.17

Antimicrobial appropriateness, n (%)92 (72.4)27 (65.9)65 (75.6)0.65

SIRS: systemic inflammatory response syndrome. qSOFA: quick sequential organ failure assessment. ACLF: acute-on-chronic liver failure. CLIF-C OF: chronic liver failure consortium organ failure score.