Research Article

Ultrasound Measured Depth of Pelvic Free Fluid Correlates Well with Blood Loss Volume in Patients with Ectopic Pregnancy

Table 1

Clinical characteristics of the ectopic pregnancy patients.

CharacteristicHaemorrhage <800 ml (N = 190)Haemorrhage ≥800 ml (N = 91)
Number (%) or mean ± SD valueDifference or OR (95% CI)

Age-yr.30.91 ± 5.1930.98 ± 5.990.917−0.7 (−1.4 to 1.3)
BMIa, no. (%)
 ≤18.426 (13.7)12 (13.2)
 18.5–23.9120 (63.2)51 (56.0)0.8310.9 (0.4 to 2.0)
 24.0–27.929 (15.3)17 (18.7)0.6061.3 (0.5 to 3.2)
 ≥28.010 (5.3)4 (4.4)1.0000.9 (0.2 to 3.3)
ASAb class, no. (%)
 I123 (64.7)27 (29.7)
 II64 (33.7)47 (51.6)<0.0013.3 (1.9 to 5.9)
 III2 (1.1)16 (17.6)<0.00136.4 (7.9 to 167.9)
 IV0 (0.0)1 (1.1)0.18513.5 (0.5 to 339.6)
Mean volume of haemorrhage, ml263.84 ± 187.931694.51 ± 882.34<0.001−1430.7 (−1562.3 to −1299.0)
Previous abdominal or pelvic surgery, no. (%)101 (40.2)49 (44.5)0.7101.1 (0.7 to 1.8)
Abdominal pain, no. (%)197 (78.5)106 (96.4)0.0076.1 (1.4 to 26.84)
Ultrasonography
 Types
  TVSc only, no. (%)102 (53.7)28 (30.8)
  TASd only, no. (%)82 (43.2)63 (69.2)<0.0012.8 (1.6 to 4.8)
  Both, no. (%)6 (3.2)0 (0.0)0.3450.3 (0.0 to 5.1)
 Depth
  Superoinferior depth of hemoperitoneum by TVS, cm2.48 ± 1.514.45 ± 2.15<0.001−2.0 (−2.7 to −1.3)
  Anteroposterior depth of hemoperitoneum by TAS, cm2.55 ± 1.194.45 ± 2.56<0.001−1.9 (−2.5 to −1.3)
Surgery procedure, no. (%)
  Laparoscopy188 (98.9)88 (96.7)
  Laparotomy0 (0.0)1 (1.1)0.3216.4 (0.3 to 158.4)
Fluids infusion
  Crystoloid solution infusion, ml1086.84 ± 368.881259.34 ± 510.710.001−172.5 (−277.9 to −67.1)
  Colloid solution infusion, ml178.95 ± 261.41648.35 ± 383.65<0.001−469.4 (−546.3 to −392.6)
Blood products
  RBCe transfusion, no. (%)0 (0.0)13 (14.3)<0.00165.5 (3.8 to 1115.8)
  Plasma transfusion, no. (%)0 (0.0)7 (7.7)<0.00132.0 (1.8 to 566.4)
  Cell salvage, no. (%)2 (1.1)49 (53.8)<0.001109.7 (25.6 to 468.9)
Preoperative haemoglobin (pre-Hgbf), g/L118.56 ± 13.09101.48 ± 14.84<0.00117.1 (13.6 to 20.5)
Postoperative haemoglobin (post-Hgb), g/L104.93 ± 12.5090.48 ± 15.54<0.00114.4 (10.9 to 18.0)
Post-Hgb–Pre-Hgb, g/L−13.33 ± 10.03−11.42 ± 16.170.248−1.9 (−5.2 to 1.3)

a: BMI, body mass index; b: ASA, American Society of Anesthesiologists; c: TVS, transvaginal ultrasound; d: TAS, transabdominal ultrasound; e: RBC, red blood cell; f: Hgb, haemoglobin.