Occurrence and Impact of Gastrointestinal Bleeding and Major Adverse Cardiovascular Events during Sepsis: A 15-Year Observational Study

Table 2

Impact of complications on the composite hospital outcomes.

Complications	N	Outcome = hospital mortality			Outcome = ICU admission			Outcome = mechanical ventilation
		Event n	Event rate	Adjusted OR^¶	Event n	Event rate	Adjusted OR^¶	Event n	Event rate	Adjusted OR^¶
				(95% CI)			(95% CI)			(95% CI)
GI bleeding
No	211,718	81,766	0.39	1 (reference)	114,274	0.54	1 (reference)	69,314	0.33	1 (reference)
Yes	8364	3872	0.46	0.98 (0.93–1.03)	5638	0.67	1.30 (1.23–1.38)	3784	0.45	1.32 (1.26–1.40)
Stroke
No	216,701	84,368	0.39	1 (reference)	117,396	0.54	1 (reference)	71,426	0.33	1 (reference)
Yes	3381	1270	0.38	0.84 (0.78–0.91)	2516	0.74	2.71 (2.47–2.97)	1672	0.49	2.07 (1.90–2.25)
ICH
No	218,067	84,721	0.39	1 (reference)	118,096	0.54	1 (reference)	71,762	0.33	1 (reference)
Yes	2015	917	0.46	1.08 (0.98–1.19)	1816	0.90	8.02 (6.84–9.42)	1336	0.66	3.92 (3.52–4.40)
AMI
No	216,592	83,762	0.39	1 (reference)	116,758	0.54	1 (reference)	70,941	0.33	1 (reference)
Yes	3490	1876	0.54	1.11 (1.03–1.19)	3154	0.90	4.78 (4.21–5.42)	2157	0.62	1.99(1.84–2.16)

Adjusted OR^¶: adjusted for age, sex, insurance premium, urbanization level, and comorbidities in the logistic regression model. .