Research Article

Clinical Outcome Predictive Value of Procalcitonin in Patients Suspected with Infection in the Emergency Department

Table 1

Patient characteristics stratified by PCT group.

OverallPCT group (ng·mL−1) value
N = 852PCT < 0.1 N = 2270.1 ≤ PCT < 0.25 N = 2350.25 ≤ PCT < 0.5 N = 114PCT ≥ 0.5 N = 276

Demographic
Male gender, n (%)419 (49.2)91 (40.1)122 (51.9)61 (53.5)145 (52.5)0.0161
Female gender, n (%)433 (50.8)136 (59.9)113 (48.1)53 (46.5)131 (47.5)
Age, mean (SD)61.7 (22.6)52.9 (22.3)59.1 (23.2)63.5 (22.7)67.3 (20.2)<0.0001

Nurse triage level and vital signs
French 1 or 2, n (%)90 (10.6)23 (10.1)23 (9.8)11 (9.6)33 (12.0)0.8266
Temperature, °C, mean (SD)37.5 (1.2)37.2 (1.1)37.6 (1.1)37.6 (1.2)37.8 (1.3)<0.0001
SBP, mmHg, mean (SD)128.4 (24.4)131.2 (22.2)131.7 (21.6)131.1 (23.2)122.3 (27.8)<0.0001
DPB, mmHg, mean (SD)73.0 (16.6)76.4 (15.7)73.9 (14.6)74.2 (15.3)69.1 (18.6)<0.0001
Heart rate, bpm, mean (SD)96.6 (23.0)93.7 (22.0)98.0 (22.7)95.5 (21.5)98.4 (24.6)0.0981
Pulse oximetry, %, mean (SD)94.1 (6.8)95.3 (6.2)94.3 (6.5)93.5 (7.2)93.4 (7.1)<0.0001
GCS, mean (SD)14.7 (1.4)14.8 (1.0)14.9 (0.8)14.5 (2.0)14.6 (1.7)0.0508

Comorbidities
Diabetes, n (%)210 (24.7)37 (16.3)51 (21.7)31 (27.2)91 (33.0)0.0001
Immunosuppression, n (%)66 (7.8)24 (10.6)12 (5.1)6 (5.3)24 (8.7)0.1040
Obesity, n (%)116 (13.6)24 (10.6)32 (13.6)16 (14.0)44 (15.9)0.3803

Infection site<0.0001
Bronchopulmonary, n (%)264 (31.0)57 (21.6)86 (32.6)35 (13.3)86 (32.6)
Urogenital, n (%)177 (20.8)37 (20.9)36 (20.3)26 (14.7)78 (44.1)
Intra-abdominal, n (%)114 (13.4)27 (23.7)40 (35.1)14 (12.3)33 (28.9)
Skin and soft tissue, n (%)75 (8.8)27 (36.0)13 (17.3)9 (12.0)26 (34.7)
Other (specified), n (%)89 (10.4)35 (39.3)16 (18.0)12 (13.5)26 (20.3)
Undetermined, n (%)133 (15.6)44 (33.1)44 (33.1)18 (13.5)27 (20.3)

Biology
CRP, mg·L−1, median (IQR)63.7 (125.9)16.6 (42.8)50.5 (96.0)89.7 (146.5)133.0 (208.2)<0.0001
Leukocytes, .109 cells. L−1, median (IQR)12.2 (7.8)10.9 (6.1)11.9 (6.3)12.2 (7.6)14.6 (10.2)<0.0001
Neutrophils, .109 cells. L−1, median (IQR)11.0 (7.6)8.2 (5.7)9.5 (6.3)10.0 (8.0)12.7 (9.4)<0.0001

CRP, C-reactive protein; DPB, diastolic blood pressure; FRENCH, French Emergency Nurses Classification in Hospital scale; GCS, Glasgow coma scale; IQR, interquartile range; PCT, procalcitonin; SBP, systolic blood pressure; SD, standard deviation.