Clinical Outcome Predictive Value of Procalcitonin in Patients Suspected with Infection in the Emergency Department

Table 2

Association of initial procalcitonin levels and clinical outcomes in univariate and multivariate logistic regression models.

		Events N (%)	Unadjusted model OR (95% CI)	Adjusted model ‡ OR (95% CI)
In-hospital mortality		82 (9.6)
PCT cut-offs
PCT < 0.1		7 (8.5)	1	1
0.1 ≤ PCT < 0.25		14 (17.1)	1.99 (0.79–5.03),	1.70 (0.65–4.23),
0.25 ≤ PCT < 0.5		13 (15.9)	4.05 (1.57–10.45),	3.24 (1.22–8.63),
PCT ≥ 0.5		48 (58.5)	6.62 (2.93–14.94),	5.10 (2.19–11.87),
ICU admission		78 (9.2)
PCT cut-offs
PCT < 0.1		10 (12.8)	1	1
0.1 ≤ PCT < 0.25		13 (16.7)	1.27 (0.55–2.96),	1.12 (0.47–2.68),
0.25 ≤ PCT < 0.5		8 (10.3)	1.64 (0.63–4.27),	1.60 (0.60–4.26),
PCT ≥ 0.5		47 (60.3)	4.45 (2.20–9.03),	4.37 (2.08–9.16),
Bacteremia		74 (8.7)
PCT cut-offs
PCT < 0.1		7 (9.5)	1	1
0.1 ≤ PCT < 0.25		11 (14.9)	1.54 (0.59–4.05),	1.75 (0.65–4.74),
0.25 ≤ PCT < 0.5		9 (12.2)	2.69 (0.98–7.43),	2.64 (0.92–7.59),
PCT ≥ 0.5		47 (63.5)	6.45 (2.85–14.58),	6.38 (2.67–15.24),
Septic shock		56 (6.6)
PCT cut-offs
PCT < 0.1		5 (8.9)	1	1
0.1 ≤ PCT < 0.25		3 (5.4)	0.57 (0.14–2.43),	0.50 (0.12–2.16),
0.25 ≤ PCT < 0.5		6 (10.7)	2.47 (0.74–8.26),	2.04 (0.60–6.99),
PCT ≥ 0.5		42 (75.0)	7.97 (3.10–20.51),	6.38 (2.41–16.86),

CI, confidence interval; ICU, intensive care unit; OR, odds ratios; PCT, procalcitonin. ‡ Adjustment for gender, age, comorbidities, and infection site.