The Role of Dectin-1-Mediated M1 Macrophage Polarization in Cerebral Ischemia-Reperfusion Injury

Figure 3

Dectin-1 was involved in cerebral infarction after cerebral ischemia-reperfusion injury by mediating apoptosis. (a) The sham-operated group and the middle cerebral artery occlusion (MCAO) group (after 6 hours, 12 hours, and 24 hours). Dectin-1, Bax, and cleaved caspase-3 increased, and antiapoptosis molecule, Bcl-2, decreased at three appropriate time points compared to the sham-operated group. (b) The quantitative analysis of western blot.

(a)

(b)