Aluminum Poisoning with Emphasis on Its Mechanism and Treatment of Intoxication

Figure 1

Pathophysiology and clinical manifestations of aluminum toxicity. Aluminum toxicity affects different body organs, including brain, parathyroid gland, kidney, lungs, liver, bones, and bone marrow, leading to various clinical manifestations. Aluminum effect on bone marrow leads to the formation of abnormal red blood cells besides its effect parathyroid gland and on musculoskeletal system is represented by abnormalities like osteoporosis and osteomalacia. Liver stenosis and nephrotic syndrome are other important manifestations of aluminum toxicity. Brain and respiratory system can also be severely damaged, followed by aluminum poisoning. Memory loss, tremor, jerk, and death are important manifestations of brain injury. Lung injury can be represented by different clinical manifestations such as asthma and chronic bronchitis (created with BioRender.com).