Development of a Novel Nomogram Incorporating Red Blood Cell Distribution Width-Albumin Ratio for the Prediction of 30-day Mortality in Acute Pancreatitis Patients
Table 1
Baseline characteristics of patients with acute pancreatitis.
Variables
All (n = 487)
Training cohort (n = 338)
Validation cohort (n = 149)
Value
Demographics
Age (year)
58.95 (47.16 ∼ 72.35)
59.48 (47.79 ∼ 73.86)
58.2 (45.5 ∼ 70.71)
0.199
Gender (n, %)
0.301
Female
215 (44.1%)
144 (42.6%)
71 (47.7%)
Male
272 (55.9%)
194 (57.4%)
78 (52.3%)
Prognostic scoring system
APS III
53 (37 ∼ 81)
52 (37 ∼ 82)
53 (37 ∼ 77)
0.974
SOFA
5 (3 ∼ 10)
5 (3 ∼ 10)
6 (2 ∼ 9)
0.773
OASIS
34 (27 ∼ 42)
34 (27 ∼ 42)
33 (27 ∼ 41)
0.462
Vital signs
Heart rate (beats/min)
114 (98 ∼ 130)
114 (98 ∼ 130)
114 (99 ∼ 130)
0.782
MBP (mmHg)
106 (93 ∼ 119)
105 (93 ∼ 119)
106 (94 ∼ 117)
0.865
Breath rate (breath/min)
28 (24 ∼ 33)
29 (24 ∼ 34)
28 (24 ∼ 32)
0.348
T (°C)
37.5 (37 ∼ 38.17)
37.56 (37.06 ∼ 38.11)
37.39 (36.94 ∼ 38.17)
0.308
Laboratory findings
RDW (%)
14.8 (13.8 ∼ 16.1)
14.8 (13.8 ∼ 16.2)
14.8 (13.9 ∼ 16.1)
0.908
Albumin (g/dL)
3 (2.4 ∼ 3.5)
3 (2.4 ∼ 3.5)
3 (2.45 ∼ 3.4)
0.887
RA
5.07 (4.22 ∼ 6.25)
5.05 (4.14 ∼ 6.3)
5.11 (4.34 ∼ 6.15)
0.971
AST/ALT
1.42 (1 ∼ 2.13)
1.4 (0.97 ∼ 2.1)
1.46 (1.02 ∼ 2.21)
0.273
BUN (mg/dL)
24 (14 ∼ 42)
25 (14 ∼ 42)
22 (12 ∼ 41)
0.228
Creatinine (mg/dL)
1.1 (0.8 ∼ 2.2)
1.1 (0.8 ∼ 2.1)
1.1 (0.8 ∼ 2.45)
0.855
Glucose (mg/dL)
153 (114 ∼ 215)
153 (115 ∼ 217)
151 (111 ∼ 215)
0.416
Hemoglobin (g/dL)
10.4 ± 2.05
10.48 ± 2.13
10.45 ± 1.85
0.874
WBC (109/L)
13.5 (9.4 ∼ 19.6)
13.45 (9.48 ∼ 19.53)
13.7 (8.75 ∼ 19.7)
0.676
Platelet (109/L)
171 (111 ∼ 250)
174 (111.75 ∼ 259.25)
162 (108 ∼ 233)
0.503
Calcium (mmol/L)
7.7 (7.1 ∼ 8.3)
7.7 (7.1 ∼ 8.3)
7.7 (6.8 ∼ 8.28)
0.82
Sodium (mmol/L)
137 (134 ∼ 140)
137 (134 ∼ 140)
138 (134 ∼ 140)
0.338
Potassium (mmol/L)
4.3 (3.9 ∼ 4.8)
4.3 (3.9 ∼ 4.8)
4.3 (3.9 ∼ 4.85)
0.894
Bilirubin (mg/dL)
1.2 (0.6 ∼ 3)
1.2 (0.6 ∼ 3.2)
1.1 (0.6 ∼ 2.45)
0.784
Comorbidities
CHF (n, %)
87 (17.9%)
59 (17.5%)
28 (18.8%)
0.723
Chronic pulmonary disease (n, %)
114 (23.4%)
85 (25.1%)
29 (19.5%)
0.172
Liver disease (n, %)
154 (31.6%)
109 (32.2%)
45 (30.2%)
0.654
Malignant cancer (n, %)
40 (8.2%)
27 (8%)
13 (8.7%)
0.785
Diabetes (n, %)
148 (30.4%)
97 (28.7%)
51 (34.2%)
0.221
Sepsis (n, %)
324 (66.5%)
229 (67.8%)
95 (63.8%)
0.39
OASIS: Oxford acute severity of illness score; SOFA: Sequential organ failure assessment; APS III: Acute physiology score III; BUN: Blood urea nitrogen; WBC: White blood cell; RDW: Red blood cell distribution width; RA: Red blood cell distribution width-albumin ratio; CHF: Chronic heart failure.