Research Article

Development of a Novel Nomogram Incorporating Red Blood Cell Distribution Width-Albumin Ratio for the Prediction of 30-day Mortality in Acute Pancreatitis Patients

Table 1

Baseline characteristics of patients with acute pancreatitis.

VariablesAll (n = 487)Training cohort (n = 338)Validation cohort (n = 149) Value

Demographics
Age (year)58.95 (47.16 ∼ 72.35)59.48 (47.79 ∼ 73.86)58.2 (45.5 ∼ 70.71)0.199
Gender (n, %)0.301
  Female215 (44.1%)144 (42.6%)71 (47.7%)
  Male272 (55.9%)194 (57.4%)78 (52.3%)
Prognostic scoring system
 APS III53 (37 ∼ 81)52 (37 ∼ 82)53 (37 ∼ 77)0.974
 SOFA5 (3 ∼ 10)5 (3 ∼ 10)6 (2 ∼ 9)0.773
 OASIS34 (27 ∼ 42)34 (27 ∼ 42)33 (27 ∼ 41)0.462
Vital signs
 Heart rate (beats/min)114 (98 ∼ 130)114 (98 ∼ 130)114 (99 ∼ 130)0.782
 MBP (mmHg)106 (93 ∼ 119)105 (93 ∼ 119)106 (94 ∼ 117)0.865
 Breath rate (breath/min)28 (24 ∼ 33)29 (24 ∼ 34)28 (24 ∼ 32)0.348
 T (°C)37.5 (37 ∼ 38.17)37.56 (37.06 ∼ 38.11)37.39 (36.94 ∼ 38.17)0.308
Laboratory findings
 RDW (%)14.8 (13.8 ∼ 16.1)14.8 (13.8 ∼ 16.2)14.8 (13.9 ∼ 16.1)0.908
 Albumin (g/dL)3 (2.4 ∼ 3.5)3 (2.4 ∼ 3.5)3 (2.45 ∼ 3.4)0.887
 RA5.07 (4.22 ∼ 6.25)5.05 (4.14 ∼ 6.3)5.11 (4.34 ∼ 6.15)0.971
 AST/ALT1.42 (1 ∼ 2.13)1.4 (0.97 ∼ 2.1)1.46 (1.02 ∼ 2.21)0.273
 BUN (mg/dL)24 (14 ∼ 42)25 (14 ∼ 42)22 (12 ∼ 41)0.228
 Creatinine (mg/dL)1.1 (0.8 ∼ 2.2)1.1 (0.8 ∼ 2.1)1.1 (0.8 ∼ 2.45)0.855
 Glucose (mg/dL)153 (114 ∼ 215)153 (115 ∼ 217)151 (111 ∼ 215)0.416
 Hemoglobin (g/dL)10.4 ± 2.0510.48 ± 2.1310.45 ± 1.850.874
 WBC (109/L)13.5 (9.4 ∼ 19.6)13.45 (9.48 ∼ 19.53)13.7 (8.75 ∼ 19.7)0.676
 Platelet (109/L)171 (111 ∼ 250)174 (111.75 ∼ 259.25)162 (108 ∼ 233)0.503
 Calcium (mmol/L)7.7 (7.1 ∼ 8.3)7.7 (7.1 ∼ 8.3)7.7 (6.8 ∼ 8.28)0.82
 Sodium (mmol/L)137 (134 ∼ 140)137 (134 ∼ 140)138 (134 ∼ 140)0.338
 Potassium (mmol/L)4.3 (3.9 ∼ 4.8)4.3 (3.9 ∼ 4.8)4.3 (3.9 ∼ 4.85)0.894
 Bilirubin (mg/dL)1.2 (0.6 ∼ 3)1.2 (0.6 ∼ 3.2)1.1 (0.6 ∼ 2.45)0.784
Comorbidities
 CHF (n, %)87 (17.9%)59 (17.5%)28 (18.8%)0.723
 Chronic pulmonary disease (n, %)114 (23.4%)85 (25.1%)29 (19.5%)0.172
 Liver disease (n, %)154 (31.6%)109 (32.2%)45 (30.2%)0.654
 Malignant cancer (n, %)40 (8.2%)27 (8%)13 (8.7%)0.785
 Diabetes (n, %)148 (30.4%)97 (28.7%)51 (34.2%)0.221
 Sepsis (n, %)324 (66.5%)229 (67.8%)95 (63.8%)0.39

OASIS: Oxford acute severity of illness score; SOFA: Sequential organ failure assessment; APS III: Acute physiology score III; BUN: Blood urea nitrogen; WBC: White blood cell; RDW: Red blood cell distribution width; RA: Red blood cell distribution width-albumin ratio; CHF: Chronic heart failure.