Research Article

Effect of Serum Ferritin on the Prognosis of Patients with Sepsis: Data from the MIMIC-IV Database

Table 1

Comparisons of information between survivors and nonsurvivors.

Survivals (n = 1,946)Nonsurvivals (n = 505) value

Age (years)62.32 ± 17.4765.78 ± 16.43<0.001
Male (%)1,039 (53.39)279 (55.25)0.456
Emergency admissions (%)1,641 (84.33)438 (86.73)0.179
CHD (%)400 (20.55)107 (21.19)0.754
Hypertension (%)659 (33.86)166 (32.87)0.674
HF (%)604 (31.04)168 (33.27)0.337
Diabetes (%)562 (28.88)144 (28.51)0.872
CKD (%)447 (22.97)125 (24.75)0.399
Anemia (%)1,314 (67.52)293 (58.02)<0.001
HR (bpm)91.08 ± 20.6892.91 ± 20.490.076
RR (cpm)20.45 ± 5.9821.78 ± 6.47<0.001
MBP (mmHg)75.48 ± 15.4773.13 ± 17.770.002
SpO2 (%)98 (95, 100)97 (95, 100)0.026
Temperature (°C)36.96 ± 0.8336.77 ± 0.88<0.001
WBC (109/L)10.8 (7.2, 15.2)12.4 (7.9, 17.9)<0.001
Hemoglobin (g/dL)9.73 ± 1.989.60 ± 2.040.215
Creatinine (mmol/L)1.1 (0.7, 2.0)1.5 (1.0, 2.5)<0.001
Lactates (mmol/L)1.5 (1.2, 2.0)2.2 (1.5, 3.0)<0.001
SOFA score3 (2, 5)4 (3, 6)<0.001
AKI (%)1,443 (74.15)456 (90.30)<0.001
Vasopressor use (%)646 (33.20)279 (55.25)<0.001
Culture positive (%)639 (32.84)191 (37.82)0.035
Respiratory system (%)261 (13.41)92 (18.22)0.006
Urine system (%)244 (38.18)57 (29.84)0.035
Blood system (%)109 (5.60)59 (11.68)<0.001
Other system (%)189 (9.71)44 (8.74)0.495
Iron metabolism
Serum iron (μg/dL)36 (20, 63)53 (26, 85)<0.001
Transferrin (mg/dL)153 (122, 187)128 (98, 162)<0.001
TIBC (μg/dL)199 (159, 243)168 (128, 209)<0.001
Ferritin (ng/mL)430 (181, 1031)892 (352, 2281)<0.001

CHD: coronary heart disease; HF: heart failure; CKDs: chronic kidney diseases; HR: heart rate; RR: respiratory rate; MBP: mean blood pressure; WBC: white blood cell; SOFA score: the sequential organ failure assessment; ICU: intensive care unit; LOS: length of stay; AKI: acute kidney injury.