Research Article

The Potential Diagnostic and Predictive Role of HbA1c in Diabetic, Septic Patients: A Retrospective Single-Center Study

Table 1

Anthropometric data, antidiabetic therapy, and laboratory parameters of diabetic, SIRS 24 h, and SOFA 24 h septic patients.

Diabetic, septic patients
CriteriaSIRS 24 h groupSOFA 24 h group

 Number of patients (n)73 (47f/26m)34 (21f/13m)
 Age (years)72.8 ± 12.773.9 ± 12.3
 Type 2 diabetes (n)7334
Comorbidities
 Hypertension (n; %)67 (91.8)31 (91.2)
 Dyslipidemia (n; %)31 (42.5)12 (35.3)
 IHD/AMI/PCI/CABG (n; %)32 (43.8)18 (52.9)
 TIA/stroke (n; %)15 (20.6)6 (17.7)
 Peripheral arterial disease (n; %)42 (57.5)18 (52.9)
 Chronic kidney disease (n; %)27 (37.0)13 (38.2)
Antidiabetic medications
 Metformin (n; %)30 (41.1)11 (32.4)
 Sulphonyl urea (n; %)24 (32.9)10 (29.4)
 DPP4 (n; %)4 (5.5)0
 Insulin (n; %)18 (24.7)11 (32.4)
Laboratory parameters
 Glucose (mmol/l)11.5 (7.7–16.3)12.05 (8.5–19.2)
 HbA1C (%)7.47 ± 1.87.26 ± 1.9
 Urea (mmol/l)8.4 (6–12.3)9.85 (6.2–19.4)
 Creatinine (µmol/l)99 (77–137)118 (95–172)
 Glomerular filtration rate (ml/min1.73 m2)52 (38–75)42 (27–61)
 C-reactive protein (mg/l)77 (21–151.5)108 (21.3–246.3)
 AST (U/L)21 (17–33.5)25 (16–42)
 GGT (U/L)35 (21–69)40 (16–124)
 ALT (U/L)21 (14–32)21 (14–37)
 Total bilirubin (µmol/l)10 (6.5–17.4)11.2 (6.3–33.6)
 White blood cell count (G/L)15.8 ± 6.117.3 ± 7.3
 Red blood cell count (T/L)4.3 ± 0.74.3 ± 0.7
 Hemoglobin concentration (g/l)129.8 ± 22.3133.8 ± 19.4
 Thrombocyte (G/L)252.6 ± 76.9251.0 ± 92.8
 Length of hospital stay (day)8 (6–11.5)8 (7–11.5)

Data are presented as mean ± standard deviation or median (lower-upper quartile).