Research Article

The Effect of Mesenchymal Stromal Cells on the Mortality of Patients with Sepsis and Septic Shock: A Promising Therapy

Table 2

Comparison of changes in laboratory tests of ADMSCs treatment and control groups by days.

Laboratory testsMSC transplantation group (n = 10)Control group (n = 20)

0 days
CRP (mg/mL)207 (32–334)100 (16–313)0.031
PCT (mg/mL)3.64 (0.65–100.0)1.17 (0.07–24.0)0.009
Laktat (mmol/L)1.42 (0.82–3.17)1.69 (0.80–9.96)0.350
WBC (103/μl)17100 (3070–41800)12230 (680–24700)0.074
AST (μ/L)49 (19–158)26 (10–2205)0.231
ALT (μ/L)34 (3–861)19 (5–1437)0.713
Platelet (103/μl)156000 (26000–479000)200500 (18000–575000)0.373
5 days
CRP (mg/mL)82 (20–275)64 (11–185)0.562
PCT (mg/mL)2.24 (0.48–100.0)0.50 (0.40–1.78)0.777
Laktat (mmol/L)1.31 (0.63–2.84)1.23 (0.54–2.54)0.974
WBC (103/μl)11190 (1990–40310)9200 (3620–24400)0.232
AST (μL)33 (10–88)25 (10–56)0.367
ALT (μL)25 (2–134)14 (4–185)0.643
Platelet (103/μl)214000 (35000–925000)159000 (19810–430000)0.285
14 days
CRP (mg/mL)62 (22–295)105 (84–36)0.287
PCT (mg/mL)1.21 (0.27–7.56)1.14 (0.98–1.30)0.909
Laktat (mmol/L)1.44 (0.80–2.43)0.93 (0.63–2.38)0.181
WBC (103/μl)9530 (1750–52230)8150 (3490–13500)0.274
AST (μL)31 (7–124)36 (19–55)0.768
ALT (μL)24 (4–169)14 (13–21)0.440
Platelet (103/μl)190000 (40000–791000)214000 (21000–385000)0.813

ADMSCs: allogenic adipose-derived MSCs.