Clinical Value of FeNO for Pulmonary Hypertension Diagnosis in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Table 1
Baseline characteristics.
AECOPD (n = 56)
AECOPD + PH (n = 27)
t/χ2
value
Male
34 (60.7%)
15 (55.5%)
0.200
0.654
Age (years)
67.91 ± 6.95
68.11 ± 6.74
−0.124
0.901
Smoker
35 (62.5%)
19 (70.3%)
0.496
0.481
GOLD grade
2.743
0.254
Grade 1
0
0
—
—
Grade 2
29 (51.8%)
10 (37.0%)
—
—
Grade 3
26 (46.4%)
15 (55.6%)
—
—
Grade 4
1 (1.7%)
2 (7.4%)
—
—
PASP (mmHg)
Mild
—
44.00 ± 5.87
—
—
Moderate
—
52.50 ± 4.50
—
—
Severe
—
69.75 ± 6.65
—
—
Arterial blood pH
7.35 ± 0.05
7.31 ± 0.09
2.339
0.025
PO2 (mmHg)
60.10 ± 6.99
53.76 ± 6.52
3.957
<0.001
PCO2 (mmHg)
56.76 ± 15.64
64.40 ± 21.04
−1.859
0.067
CRP (mg/L)
54.26 ± 26.31
90.24 ± 54.47
−3.254
0.003
BNP (pg/ml)
156.32 ± 93.25
8721.00 ± 8128.70
−3.707
0.001
Hospital stays (days)
8.64 ± 2.26
13.22 ± 3.29
−6.535
<0.001
Invasive mechanical ventilation
5 (8.9%)
7 (25.9%)
4.256
0.039
FeNO (ppb)
33.14 ± 13.38
18.78 ± 7.94
5.430
0.022
Data are shown in (%) or mean ± SD. PO2, arterial oxygen partial pressure; PCO2, arterial partial pressure of carbon dioxide; CRP, C-reactive protein; BNP, brain natriuretic peptide.
