Risk Factors for Mortality in Sepsis Patients without Lactate Levels Increasing Early
Table 1
The comparison of baseline data between hospital survivors with nonsurvivors.
Variables
Hospital nonsurvivors (n = 418)
Hospital survivors (n = 412)
value
Male (%)
272 (65.1)
249 (60.4)
0.167c
Age (years)
66 (54–75)
58 (50–71)
<0.001b
Weight (kg)
64.5 (55–70)
65 (55–70)
0.169b
Hospital stay (days)
14 (6–26)
19 (13–31.75)
<0.001b
ICU stay (days)
8 (3–16)
8 (4–13)
0.903b
Drinking history, yes (%)
48 (11.5)
48 (11.7)
0.940c
Smoking history, yes (%)
57 (13.6)
49 (11.9)
0.452c
Underlying disease, yes (%)
Hypertension
156 (37.3)
150 (36.4)
0.785c
Diabetes
90 (21.5)
89 (21.6)
0.980c
Chronic liver disease
22 (5.3)
25 (6.1)
0.616c
Chronic kidney disease
48 (11.5)
31 (7.5)
0.052c
Chronic respiratory disease
30 (7.2)
28 (6.8)
0.830c
Cardiovascular disease
93 (22.2)
68 (16.5)
0.036c
Autoimmune disease
37 (8.9)
27 (6.6)
0.215c
Malignancy
104 (24.9)
49 (11.9)
<0.001c
Cerebrovascular disease
76 (18.2)
60 (14.6)
0.222c
Types of underlying disease ≥ 2
190 (45.5)
151 (36.7)
0.010c
Use of vasoactive drugs (%)
400 (95.7)
321 (77.9)
<0.001c
Use of glucocorticoid (%)
190 (45.5)
98 (23.8)
<0.001c
Mechanical ventilation (%)
378 (90.4)
226 (54.9)
<0.001c
CRRT (%)
179 (42.8)
77 (18.7)
<0.001c
APACHE II score
23 (19–27)
17 (13–22)
<0.001b
SOFA score
10 (8–13)
8 (5.25–11)
<0.001b
GCS score
3 (3–13)
13.5 (3–15)
<0.001b
at-test and the corresponding data were expressed as mean ± SD. bNonparametric test: Mann-WhitneyU test and the corresponding data were expressed as median (interquartile range). cChi-square tests and the corresponding data were expressed as numbers (percentages). CRRT, continuous renal replacement therapy; APACHE II, acute physiology and chronic health evaluation II; SOFA, sepsis-related organ failure assessment; GCS, Glasgow coma scale.
