Research Article
Risk Factors for Mortality in Sepsis Patients without Lactate Levels Increasing Early
Table 3
Multivariate analysis of predictive factors for lactate level in sepsis patients.
| | B value | 95% CI of B value | T | value | Lower limit | Upper limit |
| (Constant) | 5.262 | 3.244 | 7.280 | 5.118 | <0.001 | APACHE II score | 0.066 | 0.030 | 0.102 | 3.607 | <0.001 | SOFA score | 0.026 | −0.048 | 0.100 | 0.689 | 0.491 | PLT | 0.001 | −0.001 | 0.003 | 0.697 | 0.486 | PT | −0.001 | −0.009 | 0.008 | −0.174 | 0.862 | APTT | 0.016 | 0.006 | 0.026 | 3.058 | 0.002 | TBIL | 0.005 | 0.001 | 0.009 | 2.517 | 0.012 | LDH | 0.000 | 0.000 | 0.000 | 5.599 | <0.001 | eGFR | −0.005 | −0.011 | 0.002 | −1.493 | 0.136 | CRE | −0.002 | −0.003 | 0.000 | −2.088 | 0.037 | Refractory hypotension | −0.819 | −1.238 | −0.400 | −3.837 | <0.001 | Use of vasoactive drugs | −0.273 | −0.892 | 0.346 | −0.865 | 0.387 | Use of glucocorticoid | −0.391 | −0.805 | 0.023 | −1.855 | 0.064 | Mechanical ventilation | 0.095 | −0.441 | 0.631 | 0.348 | 0.728 | CRRT | −1.356 | −1.826 | −0.886 | −5.660 | <0.001 | Chronic liver disease | 0.736 | −0.110 | 1.582 | 1.707 | 0.088 | Chronic kidney disease | −0.923 | −1.653 | −0.194 | −2.484 | 0.013 | Autoimmune disease | 0.311 | −0.428 | 1.049 | 0.826 | 0.409 | Malignancy | 0.174 | −0.319 | 0.668 | 0.694 | 0.488 |
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APACHE II, acute physiology and chronic health evaluation II; SOFA, sepsis-related organ failure assessment; PLT, platelet count; PT, prothrombin time; APTT, activated partial thromboplastin time; TBIL, total bilirubin; LDH, lactate dehydrogenase; CRE, creatinine; eGFR, estimated glomerular filtration rate; CRRT, continuous renal replacement therapy. In the multiple linear regression model, adjusted R2 = 0.232, F = 14.940, < 0.001. |