Risk Factors for Mortality in Sepsis Patients without Lactate Levels Increasing Early

Table 5

Organ dysfunction and clinical outcome comparison of patients in the high lactate group and the low lactate group.

	Low lactate n = 394	High lactate n = 436	value
Hospital stay (days)	18 (11–30)	15 (8–27)	<0.001^a
ICU stay (days)	8 (4–15)	7 (3–14)	0.018^a
Hospital mortality (%)	150 (38.1)	268 (61.5)	<0.001^b
APACHE II score	18 (13–23)	22 (18–26)	<0.001^a
SOFA score	8 (5–11)	10 (8–13)	<0.001^a
PT (S)	15.6 (14.4–17.3)	17.4 (15.6–20.4)	<0.001^a
APTT (S)	42.2 (37.0–49.5)	45.3 (38.8–54.4)	<0.001^a
TBIL (μmol/L)	16.95 (10.80–30.64)	23 (13.25–40.97)	<0.001^a
CRE (μmol/L)	100.2 (61.6–205.5)	126.6 (79.15–244.75)	0.001^a
Refractory hypotension	139 (35.3)	233 (53.4)	<0.001^b
CRRT	90 (22.8)	166 (38.1)	<0.001^b

^aNonparametric test: Mann-WhitneyU test. And the corresponding data were expressed as median (interquartile range). ^bChi-square tests and the corresponding data were expressed as numbers (percentages). APACHE II, acute physiology and chronic health evaluation II; SOFA, sepsis-related organ failure assessment; PT, prothrombin time; APTT, activated partial thromboplastin time; TBIL, total bilirubin; CRE, creatinine; CRRT, continuous renal replacement therapy.