Research Article

Selecting Hub Genes and Predicting Target Genes of microRNAs in Tuberculosis via the Bioinformatics Analysis

Table 3

Gene ontology analysis of common upregulated and downregulated DEGs.

CategoryTermCountGene ratio value

Upregulated
 CCGO:0016528∼sarcoplasm38.33E − 024.14E − 04
Downregulated
 BPGO:0002446∼neutrophil-mediated immunity242.07E − 013.68E − 15
 BPGO:0042119∼neutrophil activation242.07E − 013.85E − 15
 BPGO:0043312∼neutrophil degranulation231.98E − 012.01E − 14
 BPGO:0002283∼neutrophil activation involved in immune response231.98E-012.29E − 14
 BPGO:0032496∼response to lipopolysaccharide131.12E − 011.08E − 07
 BPGO:0002237∼response to a molecule of bacterial origin131.12E − 012.14E − 07
 BPGO:0042742∼defense response to a bacterium121.03E − 011.41E − 06
 BPGO:0002831∼regulation of response to a biotic stimulus121.03E − 011.08E − 05
 BPGO:0006959∼humoral immune response119.48E − 022.28E − 05
 BPGO:1903793∼positive regulation of anion transport119.48E − 021.77E − 04
 MFGO:0004869∼cysteine-type endopeptidase inhibitor activity54.10E − 023.50E − 05
 MFGO:0001618∼virus receptor activity54.10E − 021.52E − 04
 MFGO:0140272∼exogenous protein binding54.10E − 021.62E − 04
 CCGO:0042581∼specific granule161.32E − 013.31E − 15
 CCGO:0070820∼tertiary granule131.07E − 012.88E − 11
 CCGO:0034774∼secretory granule lumen141.16E − 011.29E − 08
 CCGO:0060205∼cytoplasmic vesicle lumen141.16E − 011.51E − 08
 CCGO:0031983∼vesicle lumen141.16E − 011.63E − 08
 CCGO:0030667∼secretory granule membrane131.07E − 015.56E − 08
 CCGO:0035579∼specific granule membrane86.61E − 029.55E − 08
 CCGO:0035580∼specific granule lumen75.79E − 021.09E − 07
 CCGO:0070821∼tertiary granule membrane75.79E − 023.43E − 07
 CCGO:0005766∼primary lysosome86.61E − 025.56E − 06
 CCGO:0042582∼azurophil granule86.61E − 025.56E − 06

GO, Gene Ontology; DEGs, differentially expressed genes; BP, biological process; CC, cellular component; MF, molecular function; Count, number of DEGs.