Genetics Research

Research Article

Association between the PLTP rs4810479 SNP and Serum Lipid Traits in the Chinese Maonan and Han Populations

Table 5

Relationship between serum lipid parameters and relative factors in the Maonan and Han populations.


Lipid	Risk factor	B	Std. error	Beta	t

Maonan and Han

TC	Waist circumference	0.018	0.003	0.162	5.487	<0.001
	Age	0.007	0.002	0.106	3.688	<0.001
	Height	−0.010	0.003	−0.088	−2.987	0.003
	Diastolic blood pressure	0.005	0.002	0.066	2.293	0.022

TG	Waist circumference	0.038	0.003	0.302	11.155	<0.001
	Alcohol consumption	0.298	0.073	0.109	4.106	<0.001
	Glucose	0.069	0.022	0.082	3.142	0.002
	Diastolic blood pressure	0.008	0.003	0.081	3.024	0.003

HDL-C	Waist circumference	−0.012	0.002	−0.245	−6.804	<0.001
	Ethnic group	0.189	0.022	0.225	8.779	<0.001
	Alcohol consumption	0.135	0.033	0.128	4.045.	<0.001
	Gender	0.123	0.031	0.143	3.996	<0.001
	Age	0.003	0.001	0.090	3.163	0.002
	Body mass index	−0.010	0.004	−0.082	−2.338	0.020
	Pulse pressure	−0.002	0.001	−0.060	−2.123	0.034
	Cigarette smoking	0.067	0.033	0.067	1.987	0,047

LDL-C	Waist circumference	0.017	0.003	0.199	6.917	<0.001
	Age	0.007	0.001	0.125	4.499	<0.001
	Height	−0.009	0.003	−0.096	−3.291	0.001

ApoA1	Waist circumference	−0.003	0.001	−0.103	−2.453	0.014
	Alcohol consumption	0.152	0.019	0.264	7.792	<0.001
	Gender	0.076	0.018	0.162	4.191	<0.001
	Cigarette smoking	0.064	0.019	0.117	3.311	0.001
	Weight	−0.003	0.001	−0.127	−2.831	0.005

ApoB	Waist circumference	0.006	0.001	0.280	10.346	<0.001
	Age	0.002	0.000	0.136	4.914	<0.001
	Diastolic blood pressure	0.001	0.000	0.073	2.624	0.009
	Glucose	0.010	0.004	0.065	2.399	0.017

ApoA1/ApoB	Waist circumference	−0.014	0.002	−0.244	−6.668	<0.001
	Alcohol consumption	0.214	0.038	0.180	5.552	<0.001
	Gender	0.161	0.035	0.166	4.532	<0.001
	Age	−0.003	0.001	−0.082	−3.065	0.002
	Body mass index	−0.015	0.005	−0.107	−2.998	0.003
	Cigarette smoking	0.089	0.039	0.079	2.294	0.022
	Glucose	−0.022	0.010	−0.060	−2.234	0.026

Maonan
TC	Waist circumference	0.025	0.004	0.233	5.810	<0.001
	Age	0.011	0.003	0.165	4.291	<0.001
	Gender	0.285	0.079	0.144	3.601	<0.001

TG	Waist circumference	0.038	0.004	0.345	9.209	<0.001
	Glucose	0.084	0.029	0.106	2.904	0.004
	Diastolic blood pressure	0.007	0.003	0.089	2.367	0.018
	Alcohol consumption	0.201	0.090	0.083	2.227	0.026

HDL-C	Waist circumference	−0.014	0.002	−0.333	−8.635	<0.001
	Genotype	−0.112	0.038	−0.110	−2.971	0.003
	Alcohol consumption	0.150	0.044	0.157	3.444	0.001
	Gender	0.094	0.038	0.117	2.503	0.013

LDL-C	Waist circumference	0.023	0.004	0.262	6.566	<0.001
	Gender	0263	0.066	0.160	4.018	<0.001
	Age	0.009	0.002	0.152	3.981	<0.001

ApoA1	Waist circumference	−0.006	0.001	−0.219	−5.605	<0.001
	Alcohol consumption	0.140	0.027	0.245	5.132	<0.001
	Gender	0.101	0.026	0.211	3.909	<0.001
	Cigarette smoking	0.082	0.029	0.143	2.829	0.005
	Genotype	−0.054	0.023	−0.089	−2.361	0.019

ApoB	Waist circumference	0.008	0.001	0.385	10.056	<0.001
	Age	0.002	0.000	0.181	4.945	<0.001
	Gender	0.042	0.015	0.109	2.866	0.040

ApoA1/ApoB	Waist circumference	−0.022	0.002	−0.390	−10.608	<0.001
	Alcohol consumption	0.224	0.045	0.184	4.499	<0.001
	Age	−0.004	0.001	−0.110	−3.023	0.003

Han
TC	Diastolic blood pressure	0.011	0.003	0.128	3.153	0.002
	Age	0.006	0.003	0.098	2.478	0.013
	Body mass index	0.024	0.012	0.085	2.126	0.034

TG	Waist circumference	0.039	0.006	0.266	6.837	<0.001
	Alcohol consumption	0.370	0.114	0.123	3.249	0.001
	Diastolic blood pressure	0.008	0.004	0.077	1.995	0.046

HDL-C	Waist circumference	−0.011	0.003	−0.215	−3.871	<0.001
HDL-C	Body mass index	−0.016	0.007	−0.120	−2.159	0.031

LDL-C	Age	0.007	0.002	0.155	4.003	<0.001
LDL-C	Body mass index	0.031	0.008	0.140	3.608	<0.001

ApoA1	Alcohol consumption	0.168	0.023	0.288	7.189	<0.001
ApoA1	Weight	−0.007	0.001	−0.282	−7.052	<0.001

ApoB	Waist circumference	0.005	0.001	0.189	4.863	<0.001
	Gender	−0.100	0.018	−0.248	−5.554	<0.001
	Diastolic blood pressure	0.003	0.001	0.142	3.766	<0.001
	Glucose	0.018	0.005	0.121	3.286	0.001
	Height	−0.003	0.001	−0.121	−2.675	0.008

ApoA1/ApoB	Body mass index	−0.039	0.005	−0.275	−7.287	<0.001
	Glucose	−0.042	0.013	−0.124	−3.360	<0.001
	Gender	0.213	0.040	0.232	5.359	0.001
	Alcohol consumption	0.231	0.051	0.200	4.540	<0.001
	Diastolic blood pressure	−0.004	0.002	−0.105	−2.824	0.005

TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ApoA1: apolipoprotein A1; ApoB: apolipoprotein B; ApoA1/ApoB: the ratio of apolipoprotein A1 to apolipoprotein B; B: unstandardized coefficient; Beta: standardized coefficient.