Upregulated Solute Carrier SLC39A1 Promotes Gastric Cancer Proliferation and Indicates Unfavorable Prognosis

Figure 1

Upregulated expression of SLC39A1 in gastric adenocarcinoma. (a) The mRNA level of SLC39A1 was extracted from TCGA and GTEx datasets and plotted by GEPIA server (https://gepia.cancer-pku.cn/index.html) according to transcripts per million (TPM). The data showed that SLC39A1 mRNA level was higher in gastric adenocarcinoma (GAC) tissues than that in normal stomach tissues. (b) Kaplan–Meier progression-free survival and overall survival (c) curves were plotted using the K-M plot server (https://kmplot.com/analysis/) according to the mRNA level of SLC39A1, which implied that higher SLC39A1 helped predict worse progression-free survival and overall survival. (d) Representative IHC image showed low expression of SLC39A1 protein in adjacent stomach tissues. (e) Representative IHC image exhibited high expression of SLC39A1 protein in gastric adenocarcinoma tissues. indicates . Magnification: 400X.

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