Research Article
The Underlying Molecular Basis and Mechanisms of Venous Thrombosis in Patients with Osteomyelitis: A Data-Driven Analysis
Table 3
The top 30 hub proteins identified in the topological analysis of the PPI network of DEGs2.
| No. | Gene | Degree | Betweenness centrality | Closeness centrality |
| 1 | TP53 | 74 | 0.34740282 | 0.43589744 | 2 | IL4 | 39 | 0.0760529 | 0.38442211 | 3 | MPO | 38 | 0.05899592 | 0.37996689 | 4 | ELANE | 32 | 0.02590356 | 0.35253456 | 5 | FOS | 31 | 0.0748293 | 0.38059701 | 6 | CD86 | 31 | 0.03757972 | 0.34330591 | 7 | HP | 29 | 0.04561475 | 0.36 | 8 | SOCS3 | 27 | 0.03327054 | 0.36113297 | 9 | ICAM1 | 27 | 0.02949815 | 0.37135922 | 10 | SNRPG | 26 | 0.02319152 | 0.29105897 | 11 | ORM2 | 25 | 0.00924872 | 0.30722892 | 12 | RBX1 | 25 | 0.02116545 | 0.33874539 | 13 | ARG1 | 25 | 0.01228008 | 0.32438163 | 14 | FPR2 | 24 | 0.0214619 | 0.31808732 | 15 | UBE2D1 | 24 | 0.02571099 | 0.33675715 | 16 | CAMP | 24 | 0.00896381 | 0.32233146 | 17 | BPI | 23 | 0.00389229 | 0.29708738 | 18 | RPS15A | 22 | 0.00569474 | 0.28456293 | 19 | DEFA4 | 22 | 0.00259991 | 0.29708738 | 20 | RPS17 | 21 | 0.004417 | 0.28125 | 21 | RPS21 | 21 | 0.00432586 | 0.28039096 | 22 | RPL31 | 21 | 0.00408646 | 0.28021978 | 23 | MAPK14 | 21 | 0.04653847 | 0.3538936 | 24 | CTSG | 21 | 0.0063411 | 0.29708738 | 25 | CD79A | 21 | 0.01986526 | 0.34253731 | 26 | PLAU | 21 | 0.04559923 | 0.35334873 | 27 | RPL39 | 20 | 0.01096077 | 0.29254302 | 28 | ORM1 | 20 | 0.00663223 | 0.29404228 | 29 | NDUFA4 | 20 | 0.02048315 | 0.29479769 | 30 | LTF | 20 | 0.00846729 | 0.29517685 |
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