The Underlying Molecular Basis and Mechanisms of Venous Thrombosis in Patients with Osteomyelitis: A Data-Driven Analysis

Table 3

The top 30 hub proteins identified in the topological analysis of the PPI network of DEGs2.

No.	Gene	Degree	Betweenness centrality	Closeness centrality
1	TP53	74	0.34740282	0.43589744
2	IL4	39	0.0760529	0.38442211
3	MPO	38	0.05899592	0.37996689
4	ELANE	32	0.02590356	0.35253456
5	FOS	31	0.0748293	0.38059701
6	CD86	31	0.03757972	0.34330591
7	HP	29	0.04561475	0.36
8	SOCS3	27	0.03327054	0.36113297
9	ICAM1	27	0.02949815	0.37135922
10	SNRPG	26	0.02319152	0.29105897
11	ORM2	25	0.00924872	0.30722892
12	RBX1	25	0.02116545	0.33874539
13	ARG1	25	0.01228008	0.32438163
14	FPR2	24	0.0214619	0.31808732
15	UBE2D1	24	0.02571099	0.33675715
16	CAMP	24	0.00896381	0.32233146
17	BPI	23	0.00389229	0.29708738
18	RPS15A	22	0.00569474	0.28456293
19	DEFA4	22	0.00259991	0.29708738
20	RPS17	21	0.004417	0.28125
21	RPS21	21	0.00432586	0.28039096
22	RPL31	21	0.00408646	0.28021978
23	MAPK14	21	0.04653847	0.3538936
24	CTSG	21	0.0063411	0.29708738
25	CD79A	21	0.01986526	0.34253731
26	PLAU	21	0.04559923	0.35334873
27	RPL39	20	0.01096077	0.29254302
28	ORM1	20	0.00663223	0.29404228
29	NDUFA4	20	0.02048315	0.29479769
30	LTF	20	0.00846729	0.29517685