Triptolide Inhibits Th17 Response by Upregulating microRNA-204-5p and Suppressing STAT3 Phosphorylation in Psoriasis

<div>MiR-204-5p and STAT3 expression in triptolide-treated HaCaT cells <i>in vitro</i>. HaCaT cells were treated with 0–100 nM triptolide.(a and b) MiR-204-5p and STAT3 expressions in triptolide-treated HaCaT cells detected by RT-qPCR analysis. (c and e) Protein levels of STAT3 and p-STAT3 (Tyr705) tested by Western blot analysis. Each bar presents the mean ± standard deviation obtained from three to four separate experiments. 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Genetics Research

fig2

Figure 2

Figure 2: Triptolide Inhibits Th17 Response by Upregulating microRNA-204-5p and Suppressing STAT3 Phosphorylation in Psoriasis 